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Encyclopedia of Pathology pp 1–2Cite as

Rapid on Site Evaluation (ROSE)

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

ROSA (rapid on-site appreciation); Rapid evaluation

Definition

ROSE is a technical procedure consisting in giving a rapid (in term of minutes) microscopic evaluation (diagnosis) during the FNA procedure. It is usually performed by cytopathologists or cytotechnicians.

Principle

The main role of ROSE is to provide a rapid diagnosis and to correctly address the tissue obtained during the procedure. In case of tumors, the material is addressed for cytoblock preparation; in case of lymphomas or lymphoproliferative disease, the material is addressed fresh for flow cytometry; in case of an inflammatory process, the material is addressed to microbiology and in case special test/analysis are needed (i.e., immunohistochemistry or next generation sequencing for prognostic/predictive factors), more material is sampled from the lesion (additional passes or enrichment).

Methodology

There is great variability in technical methods for obtaining cells and to manage collected specimens....

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References and Further Reading

  • Jain, D., et al. (2018). Rapid on-site evaluation of Endobronchial ultrasound-guided Transbronchial needle aspirations for the diagnosis of lung Cancer: A perspective from members of the pulmonary pathology society. Archives of Pathology & Laboratory Medicine, 142(2), 253–262.

    Article  Google Scholar 

  • Nakajima, T., et al. (2013). Rapid on-site cytologic evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for nodal staging in patients with lung cancer. The Annals of Thoracic Surgery, 95(5), 1695–1699.

    Article  Google Scholar 

  • Pearson, L. N., Layfield, L. J., & Schmidt, R. L. (2018). Cost-effectiveness of rapid on-site evaluation of the adequacy of FNA cytology samples performed by nonpathologists. Cancer Cytopathology, 126(10), 839–845.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Synlab Pathology, Lausanne, Switzerland

    Massimo Bongiovanni

Authors
  1. Massimo Bongiovanni
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Corresponding author

Correspondence to Massimo Bongiovanni .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Bongiovanni, M. (2021). Rapid on Site Evaluation (ROSE). In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5072-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5072-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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