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Urethral Accessory Gland Carcinomas

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 15 Accesses

Synonyms

Adenocarcinoma of paraurethral accessory glands; Adenocarcinoma of periurethral accessory glands; Adenocarcinoma of urethral accessory glands

Definition

Carcinoma arising from paraurethral glands; from Skene’s glands in the female patients and from Cowper and Littrè glands in the males.

Clinical Features

  • Incidence

    Exceeding rare adenocarcinoma.

  • Age

    The rare cases have been reported in adult age.

  • Sex

    Uncommon in both the sexes.

  • Site

    In the females, the tumors are mainly in distal urethra (from Skene’s glands).

    In the males, the tumors arising in the bulbomembranous urethra (from Cowper’s glands) are more common that tumors from Littrè glands which are located in the penile urethra.

    Advanced tumors make difficult to identify with certainty the normal structures. The origin of tumor from paraurethal glands should be considered when a normal urethral mucosa is identified.

  • Treatment

    Surgical treatment should be related to the site of the tumor and stage disease. PSA level is a good...

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References and Further Reading

  • Murphy, D. P., Pantuck, A. J., Amenta, P. S., et al. (1999). Female urethral adenocarcinoma: Immunohistochemical evidence of more than 1 tissue of origin. The Journal of Urology, 161, 1881–1888.

    Article  CAS  Google Scholar 

  • Pongtippan, A., Malpica, A., Levenback, C., et al. (2003). Skene’s glands adenocarcinoma resembling prostatic adenocarcinoma. International Journal of Gynecological Pathology, 23, 71–74.

    Article  Google Scholar 

  • Raspollini, M. R., Carini, M., Montironi, R., et al. (2015). Mucinous adenocarcinoma of the male urethra: Two cases’ report and literature review. Analytical and Quantitative Cytopathology and Histopathology, 37, 267–272.

    PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Histopathology and Molecular Diagnostics, University Hospital Careggi, Florence, Italy

    Maria Rosaria Raspollini

  2. Pathology Service, Champalimaud Clinical Center, Lisbon, Portugal

    Vanessa Henriques & Antonio Lopez-Beltran

  3. Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region, Ancona, Italy

    Alessia Cimadamore & Rodolfo Montironi

  4. Unit of Anatomic Pathology, Department of Surgery, Cordoba University Medical School, Cordoba, Spain

    Antonio Lopez-Beltran

Authors
  1. Maria Rosaria Raspollini
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  2. Vanessa Henriques
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  3. Alessia Cimadamore
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  4. Rodolfo Montironi
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  5. Antonio Lopez-Beltran
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Corresponding author

Correspondence to Maria Rosaria Raspollini .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Raspollini, M.R., Henriques, V., Cimadamore, A., Montironi, R., Lopez-Beltran, A. (2020). Urethral Accessory Gland Carcinomas. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4966-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4966-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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