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Testis Collecting Duct and Rete Testis Adenocarcinoma

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Part of the book series: Encyclopedia of Pathology ((EP))

Definition

Carcinoma with glandular differentiation arising from rete testis.

Clinical Features

  • Incidence

    Rete testis carcinoma is rare.

  • Age

    Age at presentation ranges between 17 and 91 years with a peak around age 70.

  • Sex

    Male.

  • Site

    Carcinoma of the rete testis is centered in the testicular hilum.

  • Treatment

    Orchifunicolectomy.

  • Outcome

    The tumor is aggressive and may have synchronous metastases to para-aortic and iliac lymphnodes. Less commonly metastases to the lungs, liver, and bone have been reported. The prognosis is poor, with an overall 5-years survival rate of 12%. Involvement of the skin of the scrotum, penis, or perineum is reported (Nochomovitz and Orenstein 1984; Michael and Srigley 2013).

Macroscopy

Most patients present with large solid scrotal mass centered in the testicular hilum. The diameter ranges from 1 to 12 cm; size >5 cm is a poor prognostic finding. Many are multifocal and/or extending to the tunica and the spermatic cord. Pathologic reporting supports two main...

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References and Further Reading

  • Al-Obaidy, K. I., Idrees, M. T., Grignon, D. J., & Ulbright, T. M. (2019). Adenocarcinoma of the rete testis: Clinicopathologic and immunohistochemical characterization of 6 cases and review of the literature. The American Journal of Surgical Pathology. [Epub ahead of print]. https://doi.org/10.1097/PAS.0000000000001219.

    Article  Google Scholar 

  • Amin, M. B. (2005). Selected other problematic testicular and paratesticular lesions: Rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors. Modern Pathology, 18(Suppl 2), S131–S145.

    Article  Google Scholar 

  • Michael, H., & Srigley, J. (2013). Pathology of the paratesticular region. In Urological pathology (1st ed., pp. 804–854). Philadelphia: Lippincott Williams and Wilkins.

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  • Nochomovitz, L. E., & Orenstein, J. M. (1984). Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates. The American Journal of Surgical Pathology, 8(8), 625–634.

    Article  CAS  Google Scholar 

  • Paluru, S., Ulbright, T. M., Amin, M., Montironi, R., & Epstein, J. I. (2018). The morphologic spectrum of sertoliform cystadenoma of the rete testis: A series of 15 cases. The American Journal of Surgical Pathology, 42(2), 141–149.

    Article  Google Scholar 

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Correspondence to Maurizio Colecchia .

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Colecchia, M., Bertolotti, A. (2019). Testis Collecting Duct and Rete Testis Adenocarcinoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4959-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4959-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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