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Seminal Vesicle Squamous Cell Carcinoma

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  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Definition

Keratinizing squamous cell carcinoma originating in the seminal vesicles (Tabata et al. 2002; Tang et al. 2016; Wang et al. 2013; Yanagisawa et al. 2002).

Clinical Features

  • Incidence

    Four cases have been reported.

  • Age

    The patients were aged 26, 54, 61, and 69 years.

  • Sex

    Male.

  • Site

    Seminal vesicles.

  • Treatment

    Early diagnosis and treatment are crucial for primary squamous cell carcinoma of the seminal vesicle.

  • Outcome

    The young patient received complete resection of the tumor; 28 months after surgery pelvic metastases were identified. In one patient, rectal metastasis occurred 7 months after resection, despite chemotherapy, leading to death. Another patient had no evidence of disease after external beam radiation, with no recurrence 2.5 years later (Tabata et al. 2002; Tang et al. 2016; Wang et al. 2013; Yanagisawa et al. 2002).

Macroscopy

The tumors were septated cystic and solid masses measuring 4–11 cm.

Microscopy

Keratinizing squamous cell carcinoma is observed along with...

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References and Further Reading

  • Tabata, K., Irie, A., Ishii, D., Yanagisawa, N., Iwamura, M., & Baba, S. (2002). Primary squamous cell carcinoma of the seminal vesicle. Urology, 59, 445.

    Article  Google Scholar 

  • Tang, K., Sun, F. A., Tian, Y., Xiao, Y., Sun, C., & Wang, P. (2016). Primary squamous cell carcinoma of the seminal vesicle: A case report. Molecular and Clinical Oncology, 4(3), 416–418.

    Article  Google Scholar 

  • Wang, J., Yue, X., Zhao, R., Cheng, B., Wazir, R., & Wang, K. (2013). Primary squamous cell carcinoma of seminal vesicle: An extremely rare case report with literature review. International Urology and Nephrology, 45, 135–138.

    Article  CAS  Google Scholar 

  • Yanagisawa, N., Saegusa, M., Yoshida, T., & Okayasu, I. (2002). Squamous cell carcinoma arising from a seminal vesicular cyst: Possible relationship between chronic inflammation and tumor development. Pathology International, 52(3), 249–253.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region (Ancona), Ancona, Italy

    Alessia Cimadamore & Rodolfo Montironi

Authors
  1. Alessia Cimadamore
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  2. Rodolfo Montironi
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Corresponding author

Correspondence to Rodolfo Montironi .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cimadamore, A., Montironi, R. (2019). Seminal Vesicle Squamous Cell Carcinoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4937-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4937-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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