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Renomedullary Interstitial Cell Tumor of the Kidney

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Medullary fibroma

Definition

Renomedullary interstitial cell tumor is a benign renal lesion. It is still unclear whether it is a hyperplastic lesion arising in response to hypertension or a benign neoplasm.

Clinical Features

  • Incidence

    They are present in nearly 50% of adults and frequently are multiple. They are common autopsy findings (Lerman et al. 1972).

  • Age

    They affect adults and elderly. Rare in pediatric age.

  • Sex

    There is no gender predominance.

  • Site

    Renomedullary interstitial cell tumors are small lesions located in the medulla kidneys.

  • Treatment

    They are found incidentally in autopsies or nephrectomies performed for other tumors.

  • Outcome

    Renomedullary interstitial cell tumors are benign lesions.

Although renomedullary interstitial cells play a role in regulation of blood pressure, renomedullary interstitial cell tumors have no correlation with hypertension.

Macroscopy

The tumor is usually 1–5 mm in diameter as white or pale gray nodules within a renal medulla (Lerman...

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References and Further Reading

  • Caliò, A., Warfel, K. A., & Eble, J. N. (2016). Renomedullary interstitial cell tumors: Pathologic features and clinical correlations. The American Journal of Surgical Pathology, 40, 1693–1701.

    Article  Google Scholar 

  • Lerman, R. J., Pitcock, J. A., Stepherson, P., et al. (1972). Renomedullary interstitial cell tumor (formerly fibroma of the renal medulla). Human Pathology, 3, 559–568.

    Article  CAS  Google Scholar 

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Correspondence to Guido Martignoni .

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Caliò, A., Segala, D., Martignoni, G. (2019). Renomedullary Interstitial Cell Tumor of the Kidney. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4928-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4928-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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