Synonyms
Definition
Renomedullary interstitial cell tumor is a benign renal lesion. It is still unclear whether it is a hyperplastic lesion arising in response to hypertension or a benign neoplasm.
Clinical Features
Incidence
They are present in nearly 50% of adults and frequently are multiple. They are common autopsy findings (Lerman et al. 1972).
Age
They affect adults and elderly. Rare in pediatric age.
Sex
There is no gender predominance.
Site
Renomedullary interstitial cell tumors are small lesions located in the medulla kidneys.
Treatment
They are found incidentally in autopsies or nephrectomies performed for other tumors.
Outcome
Renomedullary interstitial cell tumors are benign lesions.
Although renomedullary interstitial cells play a role in regulation of blood pressure, renomedullary interstitial cell tumors have no correlation with hypertension.
Macroscopy
The tumor is usually 1–5 mm in diameter as white or pale gray nodules within a renal medulla (Lerman...
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References and Further Reading
Caliò, A., Warfel, K. A., & Eble, J. N. (2016). Renomedullary interstitial cell tumors: Pathologic features and clinical correlations. The American Journal of Surgical Pathology, 40, 1693–1701.
Lerman, R. J., Pitcock, J. A., Stepherson, P., et al. (1972). Renomedullary interstitial cell tumor (formerly fibroma of the renal medulla). Human Pathology, 3, 559–568.
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Caliò, A., Segala, D., Martignoni, G. (2019). Renomedullary Interstitial Cell Tumor of the Kidney. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4928-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_4928-1
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