Definition
Lesion composed of spindle and epithelioid histiocytes arranged in a palisaded pattern with central necrosis, in which multinucleated giant cells are also present.
Clinical Features
Incidence
It is a common finding in bladders following transurethral tumor resection.
Age
Fifth to sixth decade
Sex
Male preponderance
Site
Common in bladders following transurethral bladder resections of urothelial carcinoma (Spagnolo and Waring 1986; Eble and Banks 1990)
Most cases reported in the prostate follow transurethral resection of the prostate due to benign prostatic hyperplasia (Eyre et al. 1986). This type of granulomas is, therefore, rare, in other genitourinary locations.
Treatment
The lesion when properly diagnosed microscopically does not require treatment.
Outcome
Benign
Macroscopy
Lesions measuring 0.5–2 cm, single or multiple
Microscopy
It shows of a central...
References and Further Reading
Eble, J. N., & Banks, E. R. (1990). Post-surgical necrobiotic granulomas of urinary bladder. Urology, 35, 454–457.
Eyre, R. C., Aaronson, A. G., & Weinstein, B. J. (1986). Palisading granulomas of the prostate associated with prior prostatic surgery. The Journal of Urology, 136, 121–122.
Spagnolo, D. V., & Waring, P. M. (1986). Bladder granulomata after bladder surgery. American Journal of Clinical Pathology, 86, 430–437.
Yamada, Y. (1986). Focal palisading granuloma in the prostate and bladder: A clinicopathologic study of 88 total cystectomy specimens. Acta Pathologica Japonica, 36, 1813–1822.
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Galzerano, A., Lopez-Beltran, A., Raspollini, M.R. (2019). Postsurgical Necrobiotic Granuloma of Urinary Bladder. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4899-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_4899-1
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