Skip to main content
SpringerLink
Log in

Penile Warty-Basaloid Carcinoma

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 41 Accesses

Definition

HPV-related tumor with warty and basaloid features.

Clinical Features

  • Incidence

    It is a rare tumor.

  • Age

    It occurs in the 6th decade of life.

  • Sex

    Male.

  • Site

    It occurs as a large mass involving glans, coronal sulcus, and foreskin.

  • Treatment

    Penectomy.

  • Outcome

    It is aggressive and it behawes as basaloid carcinoma with inguinal nodal metastases in about one-half of patients, with a high mortality rate from disease (Chaux et al. 2012).

Macroscopy

Grossly the tumor is well circumscribed and yellowish white. The biphasic appearance is observed macroscopically with an exophytic papillomatous feature on the surface and solid white gray deeply infiltrating mass.

Microscopy

This tumor has more than 10% of basaloid cells that are located in superficial papillae or the deep front of invasion or in both areas. It shows koilocytosis and other characteristics features of warty carcinoma in more than 10% of the tumor mass, even in the intraepithelial variant (Fig. 1), but the predominance...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References and Further Reading

  • Chaux, A., Tamboli, P., Ayala, A., Soares, F., Rodríguez, I., Barreto, J., & Cubilla, A. L. (2010). Warty-basaloid carcinoma: Clinicopathological features of a distinctive penile neoplasm. Report of 45 cases. Modern Pathology, 23(6), 896–904.

    Article  Google Scholar 

  • Chaux, A., Velazquez, E. F., Barreto, J. E., Ayala, E., & Cubilla, A. L. (2012). New pathologic entities in penile carcinomas: An update of the 2004 World Health Organization Classification. Seminars in Diagnostic Pathology, 29(2), 59–66.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Uropathology Unit, Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy

    Maurizio Colecchia

  2. Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy

    Alessia Bertolotti

Authors
  1. Maurizio Colecchia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alessia Bertolotti
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Maurizio Colecchia .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Colecchia, M., Bertolotti, A. (2019). Penile Warty-Basaloid Carcinoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4893-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4893-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation