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Idiopathic Granulomatous Epididymitis

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Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Definition

Idiopathic granulomatous epididymitis (IGE) refers to a lesion of the epididymis requiring a period of ≥6 weeks for the duration of symptoms, while others accept a period of 3 months, with no identifiable etiology (Çek et al. 2017).

Clinical Feature

  • Incidence

    Idiopathic granulomatous epididymitis is rare.

  • Age

    It affects the adult male usually 40–59 years old.

  • Sex

    Male.

  • Site

    Typically unilateral swelling and tenderness of epididymis, usually beginning in the tail and spreading to involve the whole of the epididymis.

  • Treatment

    Some patients who were only medically treated for granulomatous orchitis have recovered, but orchidectomy in cases without a preoperatory diagnosis is the treatment of choice (Morozumi et al. 2018).

  • Outcome

    Patients with a 6 weeks or longer history of discomfort or pain in the epididymis may experience testicular pain generally without any signs of infection; induration involving the spermatic cord could be another symptom.

Macroscopy

A mass with small...

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References and Further Reading

  • Çek, M., Sturdza, L., & Pilatz, A. (2017). Acute and chronic epididymitis. European Urology Supplements, 16, 124–131.

    Article  Google Scholar 

  • Morozumi, K., Ozawa, M., Kuromoto, A., Sato, M., Hoshi, S., & Numahata, K. (2018). High orchidectomy and histopathology to differentiate granulomatous orchitis from testicular malignancy: Case report and literature review. Hinyokika Kiyo, 64(2), 75–78.

    PubMed  Google Scholar 

  • Nistal, M., Mate, A., & Paniagua, R. (1997). Granulomatous epididymal lesion of possible ischemic origin. American Journal of Surgical Pathology, 21(8), 951–956.

    Article  CAS  Google Scholar 

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Correspondence to Maurizio Colecchia .

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Colecchia, M., Bertolotti, A. (2019). Idiopathic Granulomatous Epididymitis. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4828-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4828-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

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