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Hemangioma

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 38 Accesses

Definition

Hemangioma is a benign vascular tumor.

Clinical Features

  • Incidence

    Hemangioma of the urogenital tract is rare and reports consist mainly of single cases or small series. However, hemangiomas were detected in 8.8% of kidneys removed for end-stage renal disease.

  • Age

    It occurs at all ages, including infants. The median is in the sixth decade.

  • Sex

    Hemangiomas of the kidney and the bladder occur more frequently in males.

  • Site

    Urogenital hemangiomas arise more frequently in the kidney and the bladder.

  • Treatment

    Surgery is the primary treatment. Embolization of the lesion may be considered to reduce the bleeding.

  • Outcome

    Hemangioma is a benign tumor that does not recur after complete excision.

Macroscopy

Grossly, hemangiomas appear as hemorrhagic lesions ranging in size from 0.5 to 9 cm.

Microscopy

Histologically, hemangiomasconsist of a well-demarcated but unencapsulated proliferation of variably sized blood vessels, lined by flattened endothelial cells with very scant...

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References and Further Reading

  • Bean, G. R., Joseph, N. M., Gill, R. M., Folpe, A. L., Horvai, A. E., & Umetsu, S. E. (2017). Recurrent GNAQ mutations in anastomosing hemangiomas. Modern Pathology, 30, 722–727.

    Article  CAS  Google Scholar 

  • Brown, J. G., Folpe, A. L., Rao, P., Lazar, A. J., Paner, G. P., Gupta, R., Parakh, R., Cheville, J. C., & Amin, M. B. (2010). Primary vascular tumors and tumor-like lesions of the kidney: A clinicopathologic analysis of 25 cases. The American Journal of Surgical Pathology, 34, 942–949.

    Article  Google Scholar 

  • Büttner, M., Kufer, V., Brunner, K., Hartmann, A., Amann, K., & Agaimy, A. (2013). Benign mesenchymal tumours and tumour-like lesions in end-stage renal disease. Histopathology, 62, 229–236.

    Article  Google Scholar 

  • Cheng, L., Nascimento, A. G., Neumann, R. M., et al. (1999). Hemangioma of the urinary bladder. Cancer, 86, 498–504.

    Article  CAS  Google Scholar 

  • Montgomery, E., & Epstein, J. I. (2009). Anastomosing hemangioma of the genitourinary tract: A lesion mimicking angiosarcoma. The American Journal of Surgical Pathology, 33, 1364–1369.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

    Alessandro Franchi

Authors
  1. Alessandro Franchi
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Corresponding author

Correspondence to Alessandro Franchi .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Franchi, A. (2019). Hemangioma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4822-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4822-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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