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Encyclopedia of Pathology pp 1–2Cite as

Bladder Squamous Cell Papilloma

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Keratotic papilloma

Definition

Exophytic core lined by cytologically benign squamous epithelium

Clinical Features

  • Incidence

    Uncommon finding, less than 1% of the papillary tumor of the bladder

  • Age

    It affects most commonly elderly patients (mean age of 65 years old).

  • Sex

    It affects females slightly more than males.

  • Site

    Bladder. Presentation symptoms include stress incontinence and gross hematuria (Guo et al. 2006).

  • Treatment

    Surgical resection of the papillary lesion

  • Outcome

    It is a benign tumor and rarely recurs. Squamous papilloma has been found associated with urothelial neoplasms of the bladder in a low proportion of cases and seems to add a very low risk factor for bladder cancer (Cheng et al. 2000; Guo et al. 2006).

Macroscopy

On cystectomy/cystoscopy, the lesions present as whitish plaque-like or erythematous and villous lesions (Miliaras et al. 2013; Guo et al. 2006).

Microscopy

Histologically, they are characterized by an exophytic lesion with papillary architecture,...

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References and Further Reading

  • Cheng, L., Leibovich, B. C., Cheville, J. C., et al. (2000). Squamous papilloma of the urinary tract is unrelated to condyloma acuminata. Cancer, 88, 1679–1686.

    Article  CAS  Google Scholar 

  • Guo, C. C., Fine, S. W., & Epstein, J. I. (2006). Noninvasive squamous lesions in the urinary bladder: A clinicopathologic analysis of 29 cases. The American Journal of Surgical Pathology., 30(7), 883–891.

    Article  Google Scholar 

  • Miliaras, D., Vakalopoulos, I., & Anagnostou, E. (2013). Squamous cell papilloma of the urinary bladder endoscopically mimicking cancer. Case Reports in Pathology, 2013, 486312.

    PubMed  PubMed Central  Google Scholar 

  • Wang, L., Shabaik, A., & Hansel, D. E. (2013). Squamous lesions of the bladder. Diagnostic Histopathology, 19(10), 376–380.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Pathology Service, Champalimaud Clinical Center, Lisbon, Portugal

    Vanessa Henriques & Antonio Lopez-Beltran

  2. Histopathology and Molecular Diagnostics, University Hospital Careggi, Florence, Italy

    Maria Rosaria Raspollini

  3. Department of Surgery and Pathology, University of Cordoba Medical School, Cordoba, Spain

    Antonio Lopez-Beltran

Authors
  1. Vanessa Henriques
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  2. Maria Rosaria Raspollini
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  3. Antonio Lopez-Beltran
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Corresponding author

Correspondence to Antonio Lopez-Beltran .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cite this entry

Henriques, V., Raspollini, M.R., Lopez-Beltran, A. (2019). Bladder Squamous Cell Papilloma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4787-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4787-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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