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Encyclopedia of Pathology pp 1–7Cite as

Sebaceous Carcinoma of the Breast

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Carcinomas with sebaceous differentiation; Carcinomas with skin adnexal differentiation

Definition

Infiltrative growing carcinomas of the breast exhibiting sebaceous cell differentiation in at least 50% of the invasive tumor cells. In order to classify a breast tumor as such, an extramammary tumor especially carcinomas arising from the skin adnexal structures must be excluded clinically or immunohistochemically (Acosta et al. 2018; Maia and Amendoeira 2018; Martin et al. 2017).

Clinical Features

  • Incidence

    This type of breast tumor is exceedingly rare, accounting less than 1% of all breast carcinomas. Until now, 18 cases were reported in the literature, most of them fulfilling the complete criteria for a sebaceous breast carcinoma, and some were described as invasive breast cancer with sebaceous differentiation. Difficulties in recognizing this entity requires precise knowledge and recognition of the specialized additional cell type within the infiltrating tumor cells (Acosta...

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References

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Author information

Authors and Affiliations

  1. Institute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland

    Zsuzsanna Varga & Linda Moskovszky

Authors
  1. Zsuzsanna Varga
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  2. Linda Moskovszky
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Corresponding author

Correspondence to Zsuzsanna Varga .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Varga, Z., Moskovszky, L. (2018). Sebaceous Carcinoma of the Breast. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4761-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4761-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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