Definition
In literature, an unambiguous definition and uniform criteria of intraductal papillary carcinoma is lacking. Often, it is described as a luminal epithelial neoplastic proliferation of the breast confined to the mammary ducts and lobules (also known as ductal carcinoma in situ, DCIS), characterized by a papillary growth pattern. It is considered a potential precursor lesion for breast cancer. Whether these lesions represent de novo malignant papillary epithelial proliferations or malignant epithelial populations transforming and replacing benign papillomas remains unclear.
Clinical Features
As intraductal papillary carcinoma is a morphological subtype of DCIS, the following features are derived from literature based on DCIS in general, combined with data specifically focusing on intraductal papillary carcinoma (also known as papillary DCIS).
Incidence: The incidence of DCIS has dramatically...
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References and Further Reading
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Groen, E.J., Wesseling, J. (2019). Intraductal Papillary Carcinoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4757-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_4757-1
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