Synonyms
Definition
Hamartoma is from Greek hamartia meaning “fault, defect” and -oma denoting a tumor or neoplasm. (Seth 2017). The pathological definition of a hamartoma, irrespective of site of origin, is an abnormal proliferation of tissue indigenous to the organ to create a mass or tumor. In the breast, the constituents of the mass include fat, fibrous tissue, and epithelial elements. Although previously described, Arrigoni and colleagues are given credit for increasing the awareness of the existence of a breast hamartoma (Arrigoni et al. 1971).
Clinical Features
Incidence
In the premammographic era, breast hamartomas went largely unrecognized. With the introduction of screening mammography, the realization that a hamartoma is a stand-alone pathological entity is on the rise. The incidence of hamartomas is reported to be between 0.4 and 1.15% and constitutes about 4.8% of all benign breast tumors (Wu et al. 2003)....
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References and Further Reading
Amir, R. A., & Sheikh, S. S. (2016). Breast hamartoma: A report of 14 cases of an under-recognised and under-reported entity. International Journal of Surgery Case Reports, 22, 1–4.
Anani, P. A., & Hessler, C. (1996). Breast hamartoma with invasive ductal carcinoma: Report of two cases and review of the literature. Pathology, Research and Practice, 192, 1187–1194.
Arrigoni, M. G., Dockerty, M. B., & Judd, E. S. (1971). The identification and treatment of mammary hamartomas. Surgery, Gynecology & Obstetrics, 133, 577–582.
Bowman, E., Gabriela, O., Okolı, J., Gundry, K., Rizzo, M., Gabram-Mendola, S., Manne, U., Smith, G., Pambuccian, S., & Bumpers, H. L. (2012). Pseudoangiomatous stromal hyperplasia (PASH) of the breast: A series of 24 patients. The Breast Journal, 18, 242–247.
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Tse, G. M. K., Law, B. K. B., Ma, T. K. F., Chan, A. B. W., Pang, L. M., Chu, W. C. W., & Cheung, H. S. (2002). Hamartoma of the breast: A clinicopathological review. Journal of Clinical Pathology, 55, 951–954.
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Chinyama, C.N. (2018). Hamartoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4752-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_4752-1
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