Adenosquamous Carcinoma, Lung
Mixed glandular and squamous carcinoma
An invasive carcinoma showing components of both invasive adenocarcinoma and squamous cell carcinoma. The lesser component should still comprise at least 10% of the tumor overall. Thus, adenosquamous carcinoma is a diagnosis that can only be made definitively in surgically resected cases where the whole tumor can be examined.
Adenosquamous carcinoma of the lung is a relatively rare subtype, although figures for incidence vary widely due, historically, to a range of different diagnostic criteria being used to make the diagnosis. Figures quoted range from 0.4% to 5% of lung carcinomas. Given that it is a diagnosis that may only be confirmed in surgically resected series, the true incidence in all lung cancer patients, the majority of whom never have a surgical resection, could be rather different. As with most other nonsmall cell carcinomas (NSCLC), there is an association with smoking tobacco.
References and Further Readings
- Travis, W. D., Brambilla, E., Burke, A. P., Marx, A., & Nicholson, A. N. (Eds.). (2015). WHO classification of tumours of the lung, pleura, thymus and heart. Geneva: WHO Press.Google Scholar