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Encyclopedia of Pathology pp 1–14Cite as

Hodgkin Lymphoma, Classical

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Classical Hodgkin disease

Definition

Classical Hodgkin lymphoma is a clonal lymphoproliferative disorder of B-cell origin (Kuppers 2009) composed by a relatively small number of malignant cells occurring in a reactive benign inflammatory background.

Clinical Features

Epidemiology

CHL accounts for approximately 0.6% of all new cancer cases and 15–30% of all malignant lymphomas (Nakatsuka and Aozasa 2006). The incidence of CHL is higher in industrialized nations than in developing countries. CHL shows a bimodal age of distribution, with a peak in young adult (between 15 and 35 years old) and a second peak in late life after 55 years old. CHL represents the most common subtype of malignant lymphoma in young people in the Western world. CHL is rare in children and exceptional before 3 years old. Male/female ratio is 1.5:1 in children and older adults and 1:1 in younger adult patients. The disease is more frequent in white than hispanic or black people. The incidence is also...

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References and Further Reading

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Author information

Authors and Affiliations

  1. Hematopathology and Hematology Department, Hospices Civils de Lyon/Université Lyon 1, Lyon, France

    Alexandra Traverse-Glehen, Juliette Fontaine & Hervé Ghesquières

Authors
  1. Alexandra Traverse-Glehen
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  2. Juliette Fontaine
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  3. Hervé Ghesquières
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Corresponding author

Correspondence to Alexandra Traverse-Glehen .

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Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Traverse-Glehen, A., Fontaine, J., Ghesquières, H. (2019). Hodgkin Lymphoma, Classical. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_3888-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_3888-1

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  • Print ISBN: 978-3-319-28845-1

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