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Histiocytic Neoplasma

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Encyclopedia of Pathology

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References and Further Reading

  • Allen, C.E, & Parsons, D.W. (2015). Biological and clinical significance of somatic mutations in Langerhans cell histiocytosis and related histiocytic neoplastic disorders. Hematology, American Society of Hematology Educational Programme, 2015, 559–64.

    Google Scholar 

  • Badalian-Very, G., Vergilio, J. A., Degar, B. A., Rodriguez-Galindo, C., & Rollins, B. J. (2012). Recent advances in the understanding of Langerhans cell histiocytosis. British Journal of Haematology, 156, 163–172.

    Article  CAS  Google Scholar 

  • Beasley, M. B. (2010). Smoking-related small airway disease – a review and update. Advances in Anatomic Pathology, 17, 270–276.

    Article  Google Scholar 

  • Benharroch, D., Guterman, G., Levy, I., & Shaco-Levy, R. (2010). High content of Langerhans cells in malignant lymphoma – incidence and significance. Virchows Archives, 457, 63–67.

    Article  Google Scholar 

  • Boerkamp, K. M., van der Kooij, M., van Steenbeek, F. G., et al. (2013). Gene expression profiling of histiocytic sarcomas in a canine model: The predisposed flatcoated retriever dog. PLoS One, 8, e71094.

    Article  CAS  Google Scholar 

  • Campochiaro C, Tomelleri A, Cavalli G, et al. (2015). Erdheim-Chester disease. European Journal of Internal Medicine, 26, 223–229.

    Google Scholar 

  • Chan, J. K., Lamant, L., Algar, E., et al. (2008). ALK+ histiocytosis: A novel type of systemic histiocytic proliferative disorder of early infancy. Blood, 112, 2965–2968.

    Article  CAS  Google Scholar 

  • Chen, W., Jaffe, R., Zhang, L., et al. (2013). Langerhans cell sarcoma arising from chronic lymphocytic lymphoma/small lymphocytic leukemia: Lineage analysis and BRAF V600E mutation study. North American Journal of Medical Sciences, 5, 386–391.

    Article  Google Scholar 

  • Cohen-Aubart, F., Emile, J. F., Maksud, P., et al. (2014). Marked efficacy of vemurafenib in suprasellar Erdheim-Chester disease. Neurology, 83, 1294–1296.

    Article  Google Scholar 

  • Dalia, S., Jaglal, M., Chervenick, P., Cualing, H., & Sokol, L. (2014a). Clinicopathologic characteristics and outcomes of histiocytic and dendritic cell neoplasms: The Moffitt cancer center experience over the last twenty-five years. Cancers, 6, 2275–2295.

    Article  Google Scholar 

  • Dalia, S., Shao, H., Sagatys, E., Cualing, H., & Sokol, L. (2014b). Dendritic cell and histiocytic neoplasms: Biology, diagnosis, and treatment. Cancer Control, 21, 290–300.

    Article  Google Scholar 

  • Donadieu, J., Chalard, F., & Jeziorski, E. (2012). Medical management of langerhans cell histiocytosis from diagnosis to treatment. Expert Opinion on Pharmacotherapy, 13, 1309–1322.

    Article  CAS  Google Scholar 

  • Falini, B., Pileri, S., De Solas, I., et al. (1990). Peripheral T-cell lymphoma associated with hemophagocytic syndrome. Blood, 75, 434–444.

    CAS  PubMed  Google Scholar 

  • Facchetti, F., Pileri, S.A., Lorenzi, L., et al. (2017). Histiocytic and dendritic cell neoplasms: what have we learnt by studying 67 cases. Virchows Archives, 371, 467–489

    Google Scholar 

  • Feldman, A. L., Arber, D. A., Pittaluga, S., et al. (2008). Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: Evidence for trans-differentiation of the follicular lymphoma clone. Blood, 111, 5433–5439.

    Article  CAS  Google Scholar 

  • Go, H., Jeon, Y. K., Huh, J., Choi, S. J., Choi, Y. D., Cha, H. J., Kim, H. J., Park, G., Min, S., & Kim, J. E. (2014). Frequent detection of BRAF(V600E) mutations in histiocytic and dendritic cell neoplasms. Histopathology, 65, 261–272.

    Article  Google Scholar 

  • Griffin, G.K., Sholl, L.M., Lindeman, N.I., et al. (2016). Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-κB regulatory genes. Modern Pathology, 29, 67–74.

    Google Scholar 

  • Haroche, J., Charlotte, F., Arnaud, L., et al. (2012). High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses. Blood, 120, 2700–2703.

    Article  CAS  Google Scholar 

  • Hartmann, S., Döring, C., Agostinelli, C., et al. (2016). miRNA expression profiling divides follicular dendritic cell sarcomas into two groups, related to fibroblasts and myopericytomas or Castleman’s disease. European Journal of Cancer, 64, 159–66.

    Google Scholar 

  • Idbaih, A., Mokhtari, K., Emile, J. F., et al. (2014). Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib. Neurology, 83, 1478–1480.

    Article  Google Scholar 

  • Juvet, S. C., Hwang, D., & Downey, G. P. (2010). Rare lung diseases III: Pulmonary Langerhans’ cell histiocytosis. Canadian Respiratory Journal, 17, e55–e62.

    Article  Google Scholar 

  • Kairouz, S., Hashash, J., Kabbara, W., McHayleh, W., & Tabbara, I. A. (2007). Dendritic cell neoplasms: An overview. American Journal of Hematology, 82, 924–928.

    Article  Google Scholar 

  • Kansal, R., Quintanilla-Martinez, L., Datta, V., Lopategui, J., Garshfield, G., & Nathwani, B. N. (2013). Identification of the V600D mutation in exon 15 of the BRAF oncogene in congenital, benign Langerhans cell histiocytosis. Genes, Chromosomes and Cancer, 52, 99–106.

    Article  CAS  Google Scholar 

  • Laginestra, M.A., Tripodo, C., Agostinelli, C., et al. (2017). Distinctive histogenesis and immunological microenvironment based on transcriptional profiles of follicular dendritic cell sarcomas. Molecular Cancer Research, 5, 541–52.

    Google Scholar 

  • Lorenzi, L., Lonardi, S., Petrilli, G., et al. (2012). Folliculocentric B-cell-rich follicular dendritic cells sarcoma: A hitherto unreported morphological variant mimicking lymphoproliferative disorders. Human Pathology, 43, 209–215.

    Article  CAS  Google Scholar 

  • Marafioti, T., Paterson, J. C., Ballabio, E., et al. (2008). Novel markers of normal and neoplastic human plasmacytoid dendritic cells. Blood, 111, 3778–3792.

    Article  CAS  Google Scholar 

  • Méhes, G., Irsai, G., Bedekovics, J., et al. (2014). Activating BRAF V600E mutation in aggressive pediatric Langerhans cell histiocytosis: Demonstration by allele-specific PCR/direct sequencing and immunohistochemistry. American Journal of Surgical Pathology, 38, 1644–1648.

    Article  Google Scholar 

  • O’Malley, D. P., Zuckerberg, L., Smith, L. B., et al. (2014). The genetics of interdigitating dendritic cell sarcoma share some changes with Langerhans cell histiocytosis in select cases. Annals of Diagnostic Pathology, 18, 18–20.

    Article  Google Scholar 

  • Ohtake, H., & Yamakawa, M. (2013). Interdigitating dendritic cell sarcoma and follicular dendritic cell sarcoma: Histopathological findings for differential diagnosis. Journal of Clinical and Experimental Hematopathology, 53, 179–184.

    Article  Google Scholar 

  • Perkins, S. M., & Shinohara, E. T. (2013). Interdigitating and follicular dendritic cell sarcomas: A SEER analysis. American Journal of Clinical Oncology, 36, 395–398.

    Article  Google Scholar 

  • Pileri, S., & Falini, B. (1990). Peripheral T-cell lymphoma associated with hemophagocytic syndrome and hemophagocytic lymphohistiocytosis of children: Do they share something? Blood, 76, 2163–2164.

    Google Scholar 

  • Pileri, S. A., Grogan, T. M., Harris, N. L., et al. (2002). Tumours of histiocytes and accessory dendritic cells: An immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology, 41, 1–29.

    Article  CAS  Google Scholar 

  • Ratei, R., Hummel, M., Anagnostopoulos, I., et al. (2010). Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: Evidence for hematopoietic plasticity. Haematologica, 95, 1461–1466.

    Article  Google Scholar 

  • Rezk, S. A., Nathwani, B. N., Zhao, X., & Weiss, L. M. (2013). Follicular dendritic cells: Origin, function, and different disease-associated patterns. Human Pathology, 44, 937–950.

    Article  CAS  Google Scholar 

  • Roden, A. C., Hu, X., Kip, S., et al. (2014). BRAF V600E expression in Langerhans cell histiocytosis: Clinical and immunohistochemical study on 25 pulmonary and 54 extrapulmonary cases. American Journal of Surgical Pathology, 38, 548–551.

    Article  Google Scholar 

  • Sahm, F., Capper, D., Preusser, M., et al. (2012). BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis. Blood, 120, e28–e34.

    Article  CAS  Google Scholar 

  • Saygin, C., Uzunaslan, D., Ozguroglu, M., Senocak, M., & Tuzuner, N. (2013). Dendritic cell sarcoma: A pooled analysis including 462 cases with presentation of our case series. Critical Reviews in Oncology/Hematology, 88, 253–271.

    Article  Google Scholar 

  • Schuerfeld, K., Lazzi, S., de Santi, M. M., Gozzetti, A., Leoncini, L., & Pileri, S. A. (2003). Cytokeratin-positive interstitial cell neoplasm: A case report and classification issues. Histopathology, 43, 491–494.

    Article  CAS  Google Scholar 

  • Shao, H., Xi, L., Raffeld, M., Feldman, A. L., et al. (2011). Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: A study of seven cases. Modern Pathology, 24, 1421–1432.

    Article  CAS  Google Scholar 

  • Suárez-Vilela, D., Izquierdo, F. M., Méndez-Alvarez, J. R., & Escobar-Stein, J. (2012). Neoplasms of dendritic cells: Related cell origins and diagnostic markers. Fibroblastic reticulum cells and fibroblastic reticulum cell tumors show several immunophenotypic profiles. Human Pathology, 43, 1530–1531.

    Article  Google Scholar 

  • Swerdlow, S. H., Campo, E., Harris, N. L., Jaffe, E. S., Pileri, S. A., Stein, H., & Thiele, J. (Eds.). (2017). WHO classification of tumours of haematopoietic and lymphoid tissue. Revised 4th edition. Lyon: IARC Press. Chapter 17.

    Google Scholar 

  • Takahashi, E., & Nakamura, S. (2013). Histiocytic sarcoma: An updated literature review based on the 2008 WHO classification. Journal of Clinical and Experimental Hematopathology, 53, 1–8.

    Article  Google Scholar 

  • Vermi, W., Lonardi, S., Bosisio, D., et al. (2008). Identification of CXCL13 as a new marker for follicular dendritic cell sarcoma. Journal of Pathology, 216, 356–364.

    Article  CAS  Google Scholar 

  • Weiss, G. J., Alarcon, A., Halepota, M., Penny, R. J., & Von Hoff, D. D. (2010). Molecular characterization of interdigitating dendritic cell sarcoma. Rare Tumors, 2, e50.

    Article  Google Scholar 

  • Wilejto, M., & Abla, O. (2012). Langerhans cell histiocytosis and Erdheim-Chester disease. Current Opinion in Rheumatology, 24, 90–96.

    Article  CAS  Google Scholar 

  • Yousem, S. A., Dacic, S., Nikiforov, Y. E., & Nikiforova, M. (2013). Pulmonary Langerhans cell histiocytosis: Profiling of multifocal tumors using next-generation sequencing identifies concordant occurrence of BRAF V600E mutations. Chest, 143, 1679–1684.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Bologna University, Bologna, Italy

    Stefano A. Pileri

  2. European Institute of Oncology, Milan, Italy

    Stefano A. Pileri & Valentina Tabanelli

  3. Department of Experimental, Diagnostic and Specialty Medicine, Bologna University School of Medicine, Bologna, Italy

    Claudio Agostinelli

Authors
  1. Stefano A. Pileri
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  2. Valentina Tabanelli
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  3. Claudio Agostinelli
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Correspondence to Stefano A. Pileri .

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Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Pileri, S.A., Tabanelli, V., Agostinelli, C. (2018). Histiocytic Neoplasma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_3863-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_3863-1

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