Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken

HIV-Associated Lymphoid Disorders

  • Antonino CarboneEmail author
  • Annunziata Gloghini
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_3840-1



Lymphomas represent the most frequent malignancy among people infected with human immunodeficiency virus (HIV). Characteristically these lymphomas have high-grade malignancy and are in advanced stage, with extranodal involvement (Swerdlow et al. 2008). The most common lymphomas arising in the presence of HIV-associated immunosuppression include Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL). Classical Hodgkin lymphoma (cHL) is also increased in the setting of HIV, but it less frequent than BL and DLBCL. Additional lymphomas occurring in HIV-infected patients include primary effusion lymphoma (PEL) and its solid variants, lymphoma associated with Kaposi sarcoma herpesvirus (KSHV)-related multicentric Castleman disease (MCD), and plasmablastic lymphoma (PBL) of the oral cavity type (Table 1) (Carbone et al. 2016; Dolcetti et al. 2016; Said et al. 2017; Swerdlow et...
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© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Department of PathologyCentro di Riferimento Oncologico Aviano, Istituto Nazionale Tumori, IRCCSAvianoItaly
  2. 2.Department of Diagnostic Pathology and Laboratory MedicineFondazione IRCCS, Istituto Nazionale TumoriMilanItaly