Synonyms
Cystogenic ameloblastoma; Plexiform unicystic ameloblastoma; Unilocular and cystic ameloblastoma
Definition
Unicystic ameloblastoma is an uncommon variant of ameloblastoma. It exhibits several distinctive clinicopathologic features that separate it from conventional ameloblastoma, including a predilection for relatively young individuals, typically unilocular radiographic appearance, macroscopically cystic architecture, and often favorable response to conservative treatment. The unicystic ameloblastoma was first described by Robinson and Martinez, who reported a series of cystic lesions with ameloblastic epithelial lining but less aggressive clinical behavior compared to conventional solid and multicystic ameloblastoma (Robinson and Martinez 1977). These authors proposed that the lesions may have developed de novo, by neoplastic transformation of nonneoplastic odontogenic cyst lining or by cystic degeneration of a previously solid ameloblastoma.
There is some confusion and...
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Ackermann, G. L., Altini, M., & Shear, M. (1988). The unicystic ameloblastoma: A clinicopathological study of 57 cases. Journal of Oral Pathology, 17(9–10), 541–546.
Coleman, H., Altini, M., Ali, H., Doglioni, C., Favia, G., & Maiorano, E. (2001). Use of calretinin in the differential diagnosis of unicystic ameloblastomas. Histopathology, 38(4), 312–317.
Lau, S. L., & Samman, N. (2006). Recurrence related to treatment modalities of unicystic ameloblastoma: A systematic review. International Journal of Oral and Maxillofacial Surgery, 35(8), 681–690.
Li, T. J., Wu, Y. T., Yu, S. F., & Yu, G. Y. (2000). Unicystic ameloblastoma: A clinicopathologic study of 33 Chinese patients. The American Journal of Surgical Pathology, 24(10), 1385–1392.
Nodit, L., Barnes, L., Childers, E., Finkelstein, S., Swalsky, P., & Hunt, J. (2004). Allelic loss of tumor suppressor genes in ameloblastic tumors. Modern Pathology, 17(9), 1062–1067.
Philipsen, H. P., & Reichart, P. A. (1998). Unicystic ameloblastoma. A review of 193 cases from the literature. Oral Oncology, 34(5), 317–325.
Robinson, L., & Martinez, M. G. (1977). Unicystic ameloblastoma: A prognostically distinct entity. Cancer, 40(5), 2278–2285.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Chi, A. (2016). Ameloblastoma, Unicystic. In: Slootweg, P.J. (eds) Dental and Oral Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28085-1_697
Download citation
DOI: https://doi.org/10.1007/978-3-319-28085-1_697
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-28084-4
Online ISBN: 978-3-319-28085-1
eBook Packages: MedicineReference Module Medicine