Synonyms
Sialo-odontogenic cyst
Definition
The glandular odontogenic cyst is a developmental cyst of odontogenic origin that shows glandular (i.e., salivary) differentiation. It is the most recently recognized type of odontogenic cyst, first being reported in 1987.
Clinical Features
Incidence
The glandular odontogenic cyst is a rare entity that represents only 0.2 % of all odontogenic cysts.
Age
In their 2008 literature review, Kaplan and associates found that most cases occurred in young and middle-aged adults, with a mean age of 45.7 years. Fowler and colleagues reported a mean age of 51 years in their large series of 46 cases, with an age range of 20-86 years. No cases were reported during the first decade of life.
Sex
The glandular odontogenic cyst showed a slight male predominance in the literature review by Kaplan and associates, with 57 % of cases reported in men and 43 % in women. However, no sex predilection was noted in the series reported by Fowler and colleagues.
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References and Further Reading
Fowler, C. B., Brannon, R. B., Kessler, H. P., Castle, J. T., & Kahn, M. A. (2011). Glandular odontogenic cyst: analysis of 46 cases with special emphasis on microscopic criteria for diagnosis. Head and Neck Pathology, 5, 364–375.
Gardner, D. G., Kessler, H. P., Morency, R., & Schaffner, D. L. (1988). The glandular odontogenic cyst: An apparent entity. Journal of Oral Pathology & Medicine, 17, 359–366.
Kaplan, I., Gal, G., Anavi, Y., Manor, R., & Calderon, S. (2005). Glandular odontogenic cyst: Treatment and recurrence. Journal of Oral and Maxillofacial Surgery, 63, 435–441.
Kaplan, I., Anavi, Y., Manor, R., Sulkes, J., & Calderon, S. (2005). The use of molecular markers as an aid in the diagnosis of glandular odontogenic cyst. Oral Oncology, 41, 895–902.
Kaplan, I., Anavi, Y., & Hirshberg, A. (2008). Glandular odontogenic cyst: A challenge in diagnosis and treatment. Oral Diseases, 14, 575–581.
Pires, F. R., Chen, S.-Y., da Cruz Perez, D. E., de Almeida, O. P., & Kowalski, L. P. (2004). Cytokeratin expression in central mucoepidermoid carcinoma and glandular odontogenic cyst. Oral Oncology, 40, 545–551.
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© 2016 Springer-Verlag Berlin Heidelberg
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Neville, B.W. (2016). Cyst, Glandular Odontogenic. In: Slootweg, P.J. (eds) Dental and Oral Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28085-1_677
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DOI: https://doi.org/10.1007/978-3-319-28085-1_677
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