Synonyms
True cementoma
Definition
The cementoblastoma is a rare, benign neoplasm of cementoblasts. The transformed cementoblasts produce a mass of cementum (or cementum-like material) fused to the root surface of a tooth. Interestingly, cementoblastoma shares many histopathologic similarities with osteoblastoma. However, the former is clearly odontogenic, whereas the latter is osseous in origin.
Clinical Features
Incidence
The incidence is unknown. The cementoblastoma is a rare tumor. Various large-scale studies have reported the relative frequency of cementoblastoma among odontogenic tumors to range from 0.1 % to 4.2 % (Praetorius 2009).
Age
The tumor often affects young individuals, with an average age at diagnosis of 21 years. Among reported cases, there is a broad age range of 6–71 years (Brannon et al. 2002).
Sex
There is a slight male predilection, with a male-to-female ratio of 1.4:1 (Brannon et al. 2002).
Site
The majority of cases (80 %) arise in the mandible, most often in...
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References and Further Reading
Alvarez-Pérez, M. A., Narayanan, S., Zeichner-David, M., Rodriguez Carmona, B., & Arzate, H. (2006). Molecular cloning, expression and immunolocalization of a novel human cementum-derived protein (CP-23). Bone, 38(3), 409–419.
Arzate, H., Jimenez-Garcia, L. F., Alvarez-Perez, M. A., Landa, A., Bar-Kana, I., & Pitaru, S. (2002). Immunolocalization of a human cementoblastoma-conditioned medium-derived protein. Journal of Dental Research, 81(8), 541–546.
Brannon, R. B., Fowler, C. B., Carpenter, W. M., & Corio, R. L. (2002). Cementoblastoma: An innocuous neoplasm? A clinicopathologic study of 44 cases and review of the literature with special emphasis on recurrence. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 93, 311–320.
Gao, Y. H., Yang, L. J., & Yamaguchi, A. (1997). Immunohistochemical demonstration of bone morphogenetic protein in odontogenic tumors. Journal of Oral Pathology & Medicine, 26(6), 273–277.
Praetorius, F. (2009). 3.4 Cementoblastoma. In L. Barnes (Ed.), Surgical pathology of the head and neck (Vol. 3, pp. 1288–1290). New York: Informa Healthcare.
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Chi, A. (2016). Cementoblastoma. In: Slootweg, P.J. (eds) Dental and Oral Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28085-1_663
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DOI: https://doi.org/10.1007/978-3-319-28085-1_663
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