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Cementoblastoma

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Dental and Oral Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

True cementoma

Definition

The cementoblastoma is a rare, benign neoplasm of cementoblasts. The transformed cementoblasts produce a mass of cementum (or cementum-like material) fused to the root surface of a tooth. Interestingly, cementoblastoma shares many histopathologic similarities with osteoblastoma. However, the former is clearly odontogenic, whereas the latter is osseous in origin.

Clinical Features

  • Incidence

    The incidence is unknown. The cementoblastoma is a rare tumor. Various large-scale studies have reported the relative frequency of cementoblastoma among odontogenic tumors to range from 0.1 % to 4.2 % (Praetorius 2009).

  • Age

    The tumor often affects young individuals, with an average age at diagnosis of 21 years. Among reported cases, there is a broad age range of 6–71 years (Brannon et al. 2002).

  • Sex

    There is a slight male predilection, with a male-to-female ratio of 1.4:1 (Brannon et al. 2002).

  • Site

    The majority of cases (80 %) arise in the mandible, most often in...

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References and Further Reading

  • Alvarez-Pérez, M. A., Narayanan, S., Zeichner-David, M., Rodriguez Carmona, B., & Arzate, H. (2006). Molecular cloning, expression and immunolocalization of a novel human cementum-derived protein (CP-23). Bone, 38(3), 409–419.

    Article  PubMed  CAS  Google Scholar 

  • Arzate, H., Jimenez-Garcia, L. F., Alvarez-Perez, M. A., Landa, A., Bar-Kana, I., & Pitaru, S. (2002). Immunolocalization of a human cementoblastoma-conditioned medium-derived protein. Journal of Dental Research, 81(8), 541–546.

    Article  CAS  PubMed  Google Scholar 

  • Brannon, R. B., Fowler, C. B., Carpenter, W. M., & Corio, R. L. (2002). Cementoblastoma: An innocuous neoplasm? A clinicopathologic study of 44 cases and review of the literature with special emphasis on recurrence. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 93, 311–320.

    Article  PubMed  Google Scholar 

  • Gao, Y. H., Yang, L. J., & Yamaguchi, A. (1997). Immunohistochemical demonstration of bone morphogenetic protein in odontogenic tumors. Journal of Oral Pathology & Medicine, 26(6), 273–277.

    Article  CAS  Google Scholar 

  • Praetorius, F. (2009). 3.4 Cementoblastoma. In L. Barnes (Ed.), Surgical pathology of the head and neck (Vol. 3, pp. 1288–1290). New York: Informa Healthcare.

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Correspondence to Angela Chi .

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© 2016 Springer-Verlag Berlin Heidelberg

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Chi, A. (2016). Cementoblastoma. In: Slootweg, P.J. (eds) Dental and Oral Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28085-1_663

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  • DOI: https://doi.org/10.1007/978-3-319-28085-1_663

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28084-4

  • Online ISBN: 978-3-319-28085-1

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