Overview of the Current Approach to Glomerular Disease Classification

  • Juan M. Mejia-Vilet
  • Samir V. Parikh
Living reference work entry


Classification systems of disease states are created to help stratify disease to help guide clinical evaluation and treatment and provide insights into prognosis. Glomerulonephritis is a term used to broadly characterize kidney diseases that occur as a result of immunologic and inflammatory injury to the glomeruli. There are several types of glomerular diseases and these diseases can be classified based on their clinical presentation, etiology, histology, or pathogenesis. Since the incorporation of the kidney biopsy into routine practice, histopathological classification of glomerular diseases has emerged and is now most commonly used method to characterize the different glomerular lesions identified and classify the different glomerular diseases. In this chapter, we will review the current classification systems used in clinical practice to characterize and differentiate glomerular diseases.


Glomerulonephritis Glomerular disease Classification Kidney disease Kidney histology Nephritis Nephrotic syndrome IgA nephropathy Lupus nephritis Focal segmental glomerulosclerosis Histopathology 


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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Wexner Medical CenterThe Ohio State UniversityColumbusUSA
  2. 2.Department of Internal Medicine, Division of NephrologyThe Ohio State University Medical CenterColumbusUSA

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