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Tumors and Tumor-Like Lesions of the Hepatobiliary Tract pp 473–480Cite as

Variants of Hepatocellular Adenoma

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Abstract

Apart from its classical or typical form, hepatocellular adenoma (HCA) can present as one of several variants. HCA often occurs as solitary lesion, but some patients synchronously exhibit several or multiple tumors, a condition termed hepatocellular adenomatosis. Currently, adenomatosis is defined by the presence of more than ten adenomas in an otherwise normal parenchyma. Most of the former cases of telangiectatic focal nodular hyperplasia are now considered to be a variant of HCA (telangiectatic HCA) associated with systemic signs of inflammation. The majority of telangiectatic HCA exhibit inflammatory changes in the tumor. A further rare variant of HCA is pigmented HCA, solitary or multiple benign tumors having abundant Dubin-Johnson-like pigment granules in the cytoplasm.

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  1. University of Bern, Bern, Switzerland

    Arthur Zimmermann

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Zimmermann, A. (2017). Variants of Hepatocellular Adenoma. In: Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Springer, Cham. https://doi.org/10.1007/978-3-319-26956-6_25

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  • DOI: https://doi.org/10.1007/978-3-319-26956-6_25

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