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Surgical Technique of Pancreas Transplantation

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Contemporary Pancreas Transplantation

Part of the book series: Organ and Tissue Transplantation ((OTT))

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Abstract

Pancreas transplantation has become accepted as the only definitive long-term treatment that reliably restores euglycemia by restoring endogenous insulin production and improving glucose counterregulation in patients with type 1 diabetes mellitus and in carefully selected patients with insulin-dependent type 2 diabetes mellitus. Despite five decades of experience and with more than 41,000 pancreas transplants performed worldwide through 2011, a multitude of variations exist in operative technique, reflecting the lack of consensus regarding the best method for implanting a pancreas allograft into a recipient. These differences in technique are primarily related to the method of pancreatic exocrine secretion drainage and the site of portal-venous drainage. The surgical technique of pancreas transplantation has evolved over time in response to technical complications and physiologic derangements associated with earlier methods of implantation. This chapter reviews the historical development of the pancreas transplant technique and elaborates on the rationale for the different variations currently practiced. Detailed descriptions of the most common technical approaches to implantation are provided.

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Authors and Affiliations

  1. Department of Surgery, Section of Abdominal Organ Transplantation, Wake Forest Baptist Medical Center, Medical Center Blvd., Winston-Salem, NC, 27157, USA

    Muhammad Arsalan Khan, Fowler R. Smith & Jeffrey Rogers

Authors
  1. Muhammad Arsalan Khan
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  2. Fowler R. Smith
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  3. Jeffrey Rogers
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Corresponding author

Correspondence to Jeffrey Rogers .

Editor information

Editors and Affiliations

  1. Organ Transplantation, Hackensack University Medical Center Transplant Surgery and, Hackensack, New Jersey, USA

    James W. Lim

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© 2016 Springer International Publishing Switzerland

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Khan, M.A., Smith, F.R., Rogers, J. (2016). Surgical Technique of Pancreas Transplantation. In: Lim, J. (eds) Contemporary Pancreas Transplantation. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-20789-6_1-2

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  • DOI: https://doi.org/10.1007/978-3-319-20789-6_1-2

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  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-20789-6

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Chapter history

  1. Latest

    Surgical Technique of Pancreas Transplantation
    Published:
    26 July 2016

    DOI: https://doi.org/10.1007/978-3-319-20789-6_1-2

  2. Original

    Surgical Technique of Pancreas Transplantation
    Published:
    16 March 2016

    DOI: https://doi.org/10.1007/978-3-319-20789-6_1-1

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