Skip to main content

Chemical Peelings: Body

  • Living reference work entry
  • First Online:
Daily Routine in Cosmetic Dermatology

Abstract

Chemical peels have always been the most economical therapeutic modality for skin rejuvenation and classified as superficial, medium, or deep based on their depth of penetration into the epidermis and dermis. Non-facial chemical peelings are best confined to light to medium peels because of the paucity of adnexal structures. These regimens of light to medium peels may yield significant improvement but must be performed conservatively and serially over time until results are satisfactory. The results are heavily dependent on concentration, contact time with the skin, and the manner of prepeel preparation. Deeper peels confer the risk of scarring, dyschromia, creation of a demarcation line between the treated and untreated area, and prolonged erythema.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Bagatin E. 5-fluorouracil for actinic keratosis. Exp Rev Dermatol. 2010;5:131–9.

    Article  CAS  Google Scholar 

  • Bagatin E, Hassun KM, Teixeira SP, Talarico S. 5- Fluorouracil superficial peel for multiple actinic keratosis. Int J Dermatol. 2009;48:902–7.

    Article  CAS  PubMed  Google Scholar 

  • Bagatin E, Wagemaker TAL, Aguiar Jr. NR, et al. Skin penetration of tretinoin in three concentrations as an agent for superficial chemical peeling. Poster no. 1613. In: 69th Annual Meeting American Academy of Dermatology (AAD), New Orleans, February 4–8, 2011.

    Google Scholar 

  • Bernstein EF. Chemical peels. Semin Cutan Med Surg. 2002;21:27–45.

    Article  PubMed  Google Scholar 

  • Berson DS, Cohen JL, Rendon MI, et al. Clinical role and application of superficial chemical peels in today’s practice. J Drugs Dermatol. 2009;8:803–11.

    PubMed  Google Scholar 

  • Briden ME. Alpha-hydroxiacid chemical peeling agents: case studies and rationale for safe and effective use. Cutis. 2004;73:18–24.

    PubMed  Google Scholar 

  • Brody HJ. Chemical peeling. 2nd ed. St Louis: Mosby; 1997.

    Google Scholar 

  • Brody HJ, Monheit GD, Resnik S, Alt TH. A history of chemical peeling. Dermatol Surg. 2000;26:405–9.

    Article  CAS  PubMed  Google Scholar 

  • Burns RL, Prevost-Blank PL, Lawry MA, et al. Glycolic acid peels for postinflammatory hyperpigmentation in black patients. Dermatol Surg. 1997;23:171–5.

    CAS  PubMed  Google Scholar 

  • Cassano N, Alessandrini G, Mastrolonarno M, Vena GA. Peeling agents: toxicological and allergological aspects. J Eur Acad Dermatol Venereol. 1999;13:14–23.

    Article  CAS  PubMed  Google Scholar 

  • Chun EY, Lee JB, Lee KH. Focal trichloroacetic acid peel method for benign pigmented lesions in dark-skinned patients. Dermatol Surg. 2004;30:512–6.

    PubMed  Google Scholar 

  • Collins PS. Trichloroacetic acid peels revisited. J Dermatol Surg Oncol. 1989;15:933–40.

    Article  CAS  PubMed  Google Scholar 

  • Cook KK, Wr CJ. Chemical peel of nonfacial skin using glycolic acid gel augmented with TCA and neutralized based on visual staging. Dermatol Surg. 2000;26:994–9.

    Article  CAS  PubMed  Google Scholar 

  • Cook-Bolden F, Nestor M, Rodriguez M. The use of a triple-drug combination product and procedures for the treatment of hyperpigmentary disorders. Cosmetic Dermatol. 2005;18:589–94.

    Google Scholar 

  • Corcuff P, Fiat F, Minondo AM, Leveque JL, Rougier A. A comparative ultrastructural study of hydroxyacids induced desquamation. Eur J Dermatol. 2002;12:XXXIX–LIII.

    CAS  PubMed  Google Scholar 

  • Cotellessa C, Peris K, Onorati MT, et al. The use of chemical peelings in the treatment of different cutaneous hyperpigmentations. Dermatol Surg. 1999;25:450–4.

    Article  CAS  PubMed  Google Scholar 

  • Cotellessa C, Manunta T, Ghersetich I, et al. The use of pyruvic acid in the treatment of acne. J Eur Acad Dermatol Venereol. 2004;18:275–8.

    Article  CAS  PubMed  Google Scholar 

  • Cox S. Rapid development of keratoacanthomas after a body peel. Dermatol Surg. 2003;29:201–3.

    PubMed  Google Scholar 

  • Cucé LC, Bertino MCM, Scattone L, et al. Tretinoin peeling. Dermatol Surg. 2001;27:12–4.

    PubMed  Google Scholar 

  • Dinardo JC, Grove GL, Moy LS. Clinical and histological effects of glycolic acid at different concentrations and pH levels. Dermatol Surg. 1996;22:421–4.

    CAS  PubMed  Google Scholar 

  • Drake LA, Dinehart SM, Goltz RW, et al. Guidelines of care for chemical peeling. J Am Acad Dermatol. 1995;33:497–503.

    Article  CAS  PubMed  Google Scholar 

  • Fabbrocini G, Padova MP, Tosti A. Chemical peels: what’s new and what isn’t new but still works well. Facial Plast Surg. 2009;25:329–36.

    Article  CAS  PubMed  Google Scholar 

  • Fischer TC, Prosino E, Poli F, et al. Chemical peels in aesthetic dermatology: an update 2009. J Eur Acad Dermatol Venereol. 2010;24:281–92.

    Article  CAS  PubMed  Google Scholar 

  • Flynn TC, Coleman PW. Topical revitalization of body skin. J Eur Acad Dermatol Venereol. 2000;14:280–4.

    Article  CAS  PubMed  Google Scholar 

  • Fulton JE, Porumb S. Chemical peels: their place within the range of resurfacing techniques. Am J Clin Dermatol. 2004;5:179–87.

    Article  PubMed  Google Scholar 

  • Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. Dermatol Surg. 2009;35:59–65.

    CAS  PubMed  Google Scholar 

  • Ghersetich HB, Brazzini B, Peris K, et al. Pyruvic acid peels for the treatment of photoaging. Dermatol Surg. 2004;30:32–6.

    PubMed  Google Scholar 

  • Gladstone HB. Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamaged on the neck and upper chest. Dermatol Surg. 2000;26:333–7.

    Article  CAS  PubMed  Google Scholar 

  • Griffin TD, Van Scott EJ. Use of pyruvic acid in the treatment of actinic keratosis: a clinical and histopathologic study. Cutis. 1991;47:325–9.

    CAS  PubMed  Google Scholar 

  • Griffin TD, Van Scott EJ, Maddin S. The use of pyruvic acid as a chemical peeling agent. J Dermatol Surg Oncol. 1989;15:1316.

    Google Scholar 

  • Griffiths CEM, Russman NA, Majmudar G, et al. Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid). N Engl J Med. 1993;329:530–5.

    Article  CAS  PubMed  Google Scholar 

  • Grimes PE. The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups. Dermatol Surg. 1999;25:18–22.

    Article  CAS  PubMed  Google Scholar 

  • Gurvinder B, Kalpana P. Glycolic acid peels for nail rejuvenation. J Cut Aesthet Surg. 2014;7:198–201.

    Article  Google Scholar 

  • Imayama S, Ueda S, Isoda M. Histologic changes in the skin of hairless mice following peeling with salicylic acid. Arch Dermatol. 2000;136:1390–5.

    Article  CAS  PubMed  Google Scholar 

  • Jaishree S. Glycolic acid peel therapy – a current review. Clin Cosmet Investig Dermatol. 2013;6:281–8.

    Google Scholar 

  • Jasin ME. Regarding combined therapy for neck rejuvenation. Dermatol Surg. 2000;26:294–5.

    Article  CAS  PubMed  Google Scholar 

  • Karam P. 50% resorcinol peel. Int J Dermatol. 1993;32:569–74.

    Article  CAS  PubMed  Google Scholar 

  • Katz BE. The fluor-hydroxy pulse peel: a pilot evaluation of a new superficial chemical peel. Cosm Dermatol. 1995;8:24–30.

    Google Scholar 

  • Kligman DE, Draelos ZD. High-strength tretinoin for rapid retinization of photoaged facial skin. Dermatol Surg. 2004;30:864–6.

    PubMed  Google Scholar 

  • Laundau M. Chemical peels. Clin Dermatol. 2008;26:200–8.

    Article  Google Scholar 

  • Lazo ND, Meine JG, Downing DT. Lipids are covalently attached to rigid corneocyte protein envelope existing predominantly as beta-sheets: a solid state nuclear magnet resonance study. J Invest Dermatol. 1995;105:296–300.

    Article  CAS  PubMed  Google Scholar 

  • Lee HS, Kim IH. Salicylic acid peels for the treatment of acne vulgaris in Asian patients. Dermatol Surg. 2003;29:1196–9.

    PubMed  Google Scholar 

  • Marrero GM, Katz BE. The new fluor-hydroxy pulse peel. A combination of 5-fluorouracil and glycolic acid. Dermatol Surg. 1998;24:973–8.

    CAS  PubMed  Google Scholar 

  • Monheit GD. The Jessner’s + TCA peel: a medium-depth chemical peel. J Dermatol Surg Oncol. 1989;15:945–50.

    Article  CAS  PubMed  Google Scholar 

  • Monheit GD. Medium-depth chemical peels. Dermatol Clin. 2001;19:413–25.

    Article  CAS  PubMed  Google Scholar 

  • Monheit GD. Chemical peels. Skin Therapy Lett. 2004;9:6–11.

    PubMed  Google Scholar 

  • Monheit GD, Chastain MA. Chemical peels. Facial Plast Surg Clin North Am. 2001;9:239–55.

    CAS  PubMed  Google Scholar 

  • Okano Y, Abe Y, Masaki H, et al. Biological effects of glycolic acid on dermal matrix metabolism mediated by dermal fibroblasts and epidermal keratinocytes. Exp Dermatol. 2003;12(Suppl 2):57–63.

    Article  CAS  PubMed  Google Scholar 

  • Rendon MI, Berson DS, Cohen JL, et al. Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing. J Clin Aesthet Dermatol. 2010;3:32–43.

    PubMed  PubMed Central  Google Scholar 

  • Roberts WE. Chemical peeling in ethnic/dark skin. Dermatol Ther. 2004;17:196–205.

    Article  PubMed  Google Scholar 

  • Schurer NY, Wiest L. Chemical peels. Hautarzt. 2006;57:61–76.

    Article  CAS  PubMed  Google Scholar 

  • Sezer E, Erbil H, Kurumlu Z, et al. A comparative study of focal medium-depth chemical peel versus cryosurgery for the treatment of solar lentigo. Eur J Dermatol. 2007;17:26–9.

    PubMed  Google Scholar 

  • Slavin J. Rejuvenation of the hand: alternative treatments for lightening the dorsal skin. Aesthetic Surg J. 2000;20:72–3.

    Article  Google Scholar 

  • Teixeira SP, Nascimento MM, Bagatin E, et al. The use of fluor-hydroxy pulse peel in actinic porokeratosis. Dermatol Surg. 2005;31:1145–8.

    Article  CAS  PubMed  Google Scholar 

  • Tosti A, Grimes PE, De Padova MP. Color atlas of chemical peels. 2nd ed. Berlin: Springer; 2012.

    Book  Google Scholar 

  • Tung TC. Alpha-hydroxy acid-based cosmetic procedures. Guidelines for patient management. Am J Clin Dermatol. 2000;1:81–8.

    Article  CAS  PubMed  Google Scholar 

  • Uhoda E, Pierard-Franchimont C, Pierard GE. Comedolysis by a lipohydroxyacid formulation in acne-prone subjects. Eur J Dermatol. 2003;13:65–8.

    CAS  PubMed  Google Scholar 

  • Unna PG. Therapeutiques generales des maladies de la peau. 1882.

    Google Scholar 

  • Vossen M, Hage JJ, Karim RB. Formulation of trichloroacetic acid peeling solution: a bibliometric analysis. Plast Reconstr Surg. 2000;105:1088–94. discussion 1095–6

    Article  CAS  PubMed  Google Scholar 

  • Wiest L. Chemical peels in aesthetic dermatology. Hautarzt. 2004;55:611–20.

    Article  CAS  PubMed  Google Scholar 

  • Zakopoulou N, Kontochristopoulos G. Superficial chemical peels. J Cosmet Dermatol. 2006;5:246–53.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andréa Serra Rodrigues .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this entry

Cite this entry

Rodrigues, A.S., Cunha, V.M. (2016). Chemical Peelings: Body. In: Issa, M., Tamura, B. (eds) Daily Routine in Cosmetic Dermatology. Clinical Approaches and Procedures in Cosmetic Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-20250-1_36-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-20250-1_36-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20250-1

  • Online ISBN: 978-3-319-20250-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics