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Obesity: Genetics, Pathogenesis, and Therapy

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Principles of Diabetes Mellitus

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Abstract

The increasing prevalence of obesity is a major public health concern. The present epidemic is distributed across sociodemographic groups in both industrialized and developing countries. This poses tremendous clinical challenges, as obesity makes notable contributions to morbidity and mortality and carries a staggering economic cost. In this chapter, we discuss the definition, classification, and epidemiology of obesity. Furthermore, we review the genetics and pathogenesis of obesity, as well as the evaluation of the patient with obesity and the current available treatments.

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Authors and Affiliations

  1. Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Hannah Mathew, Stavroula A. Paschou, Kalliopi M. Aramapatzi, William Hsu & Christos S. Mantzoros

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  1. Hannah Mathew
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  2. Stavroula A. Paschou
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  3. Kalliopi M. Aramapatzi
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  4. William Hsu
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  5. Christos S. Mantzoros
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Correspondence to Stavroula A. Paschou .

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Editors and Affiliations

  1. Division of Endocrinology, Gerald J. Friedman Diabetes Institute, Lenox Hill Hospital, Hofstra Northwell School of Medicine, Northwell Health, New York, New York, USA

    Leonid Poretsky

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Mathew, H., Paschou, S.A., Aramapatzi, K.M., Hsu, W., Mantzoros, C.S. (2017). Obesity: Genetics, Pathogenesis, and Therapy. In: Poretsky, L. (eds) Principles of Diabetes Mellitus. Springer, Cham. https://doi.org/10.1007/978-3-319-18741-9_30

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  • DOI: https://doi.org/10.1007/978-3-319-18741-9_30

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