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Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral Agents

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Principles of Diabetes Mellitus

Abstract

Diabetes mellitus is a chronic disease involved with the dysregulation of glucose metabolism through defects in insulin production and action. Diabetes has a significant impact on multiple organ systems, including the skin. Most patients will eventually develop cutaneous manifestations of the disease. Oftentimes it is the initial presenting symptom of an underlying diagnosis of diabetes. The range of cutaneous findings is broad, ranging from idiopathic inflammatory conditions, such as granuloma annulare and necrobiosis lipoidica, to metabolic derangements of the skin seen in acanthosis nigricans and acrochordans. Neuropathic and vasculopathic changes in long-standing diabetes can lead to chronic ulcerations of the skin. Even therapeutic management of diabetes can lead to unwanted cutaneous side effects. This chapter will focus on the clinical features, pathogenesis, and treatment modalities of the various dermatologic manifestations of the diabetes.

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Authors and Affiliations

  1. Department of Dermatology, Weill Cornell Medical College, 1305 York Avenue, New York, NY, 10021, USA

    George I. Varghese & Mathew C. Varghese

  2. School of Medicine, Cornell University, New York, NY, USA

    Maliha Mathew

  3. Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Ellen Marmur

Authors
  1. George I. Varghese
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  2. Maliha Mathew
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  3. Ellen Marmur
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  4. Mathew C. Varghese
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Correspondence to George I. Varghese .

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Editors and Affiliations

  1. Division of Endocrinology, Gerald J. Friedman Diabetes Institute, Lenox Hill Hospital, Hofstra Northwell School of Medicine, Northwell Health, New York, New York, USA

    Leonid Poretsky

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Varghese, G.I., Mathew, M., Marmur, E., Varghese, M.C. (2017). Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral Agents. In: Poretsky, L. (eds) Principles of Diabetes Mellitus. Springer, Cham. https://doi.org/10.1007/978-3-319-18741-9_29

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  • DOI: https://doi.org/10.1007/978-3-319-18741-9_29

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