Hypoglycemia in Diabetes Mellitus

  • Mazen Alsahli
  • John E. GerichEmail author
Reference work entry


Hypoglycemia is a frequent occurrence for many patients with diabetes treated with insulin or insulin secretagogues. Episodes of hypoglycemia have significant morbidity and mortality and are the main limiting factor for achieving near optimal glycemic control. Risk factors including impaired glucose counterregulation and hypoglycemia unawareness are largely preventable and/or reversible. This chapter summarizes our current knowledge of the epidemiology, pathogenesis, risk factors, and complications of hypoglycemia in patients with diabetes and discusses prevention and treatment strategies.


Type 1 diabetes Type 2 diabetes Hypoglycemia Hypoglycemia counterregulation 



Chronic kidney disease


Type 1 diabetes mellitus


Type 2 diabetes mellitus


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Southlake Regional Health CenterNewmarketCanada
  2. 2.Department of MedicineUniversity of TorontoTorontoCanada
  3. 3.Department of MedicineUniversity of Rochester School of MedicineRochesterUSA

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