A History of Kidney Transplantation

  • Jerry McCauley
Living reference work entry

Latest version View entry history

Part of the Organ and Tissue Transplantation book series (OTT)


Kidney transplantation has a long rich history dating back to Indian plastic surgeon’s refashioning of deformed noses until now when hundreds of thousands of grafts have been successfully transplanted. The advances were incremental with periods in which the gains were forgotten requiring duplication and delay. Skin grafts have provided invaluable information on the immunology of transplantation and remain a standard research method. Unfortunately, the erroneous claims of successful clinical skin grafting throughout history have only recently been corrected. It is difficult to assign primacy to any one pioneer for landmark advances since in most cases the “first” of any advance followed a substantial background of previous studies and in some cases the successful transplant was not a surprise to anyone. The credit should go to the many who worked tirelessly without reward to advance renal transplantation and all other forms of transplantation for the good of their patients. We live in an era when what was myth is now reality.


Homo(allo)transplantation Hetero(xeno)transplantation Autograft Freemartin cattle Grafts Acute renal failure Immunosuppression Carrel patch Cyclosporine Imuran Tacrolimus 6-Mercaptopurine Total body irradiation (TBI) Human histocompatibility antigen (HLA) OPTN (Organ Procurement and Transplantation Network) UNOS (United Network of Organ Sharing) 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Chief Nephrology DivisionSidney Kimmel Medical College, Thomas Jefferson UniversityPhiladelphiaUSA

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