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Botulinum Toxins

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Part of the book series: Clinical Approaches and Procedures in Cosmetic Dermatology ((CAPCD,volume 1))

Abstract

Botulinum toxin (BoNT) has been used over the last 40 years in different medical specialties. Since then its use has been expanded over the decades to new indications, particularly in dermatology. It produces chemodenervation of muscles by inhibiting acetylcholine release on the neuromuscular junction and has been used in cosmetics to treat hyperfunctional and hyperdynamic lines and wrinkles of the face and neck as well as localized hyperhidrosis. It is currently recognized as a safe and effective treatment when standard techniques and recommended doses are used. Due to its mechanism of action, therapeutic doses are extremely small, the effect is highly precise, and systemic adverse effects are rare. There are five sources of botulinum toxin A (BoNT-A) worldwide, but BoNT formulations are not identical or interchangeable.

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Correspondence to Ada Regina Trindade de Almeida .

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Trindade de Almeida, A.R., Silva, Y.K. (2017). Botulinum Toxins. In: Issa, M., Tamura, B. (eds) Daily Routine in Cosmetic Dermatology. Clinical Approaches and Procedures in Cosmetic Dermatology, vol 1. Springer, Cham. https://doi.org/10.1007/978-3-319-12589-3_32

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  • DOI: https://doi.org/10.1007/978-3-319-12589-3_32

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