Immunology defines the study of all properties of the immune system including its structure and its function, the bodily distinction between self and nonself, innate and acquired immunity, and immunization. For the host defense in health and disease, it investigates especially the relationship between invading pathogens and the triggered immune responses of the organism. Immune effector mechanisms are altered in space by the unique conditions of this perilous environment (radiation, confinement, μG) together with stress hormone-related modifications. To understand the changes that occur during short- and long-term spaceflight and to counteract appropriately to prevent disease, in-flight immune monitoring will become pivotal.
General Principles of Human Host Defense
During everyday life, a human being encounters a multitude of microorganisms and potential pathogens. Disease, however, will...
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