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Peri-transplant Determinants of Outcome in Liver Transplantation

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Solid Organ Transplantation in Infants and Children

Part of the book series: Organ and Tissue Transplantation ((OTT))

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Abstract

Optimizing outcomes for children undergoing liver transplantation involves ongoing multidisciplinary assessment of medical morbidities unique to the underlying disease and specific patient population. In3reasing understanding of cardiopulmonary and renal factors as impacting posttransplant outcomes as well as high level of heterogeneity in patient diagnoses presenting for liver transplantation requires a dynamic approach in evaluation.

Technical expertise remains critical to early success of pediatric liver transplantation, and single center as well as network analysis (OPTN, SPLIT, others) has identified variation in outcomes as well as opportunities for improvement. Critical assessment and prophylaxis or intervention for infection and optimizing renal status in the early posttransplant period are critical as is timely management of surgical complications.

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Authors and Affiliations

  1. Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Armando Ganoza

  2. Division of Nephrology and Hypertension, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave., ML 7022, Cincinnati, OH, 45229, USA

    Stuart Goldstein

  3. Center for Acute Care Nephrology, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave., ML 7022, Cincinnati, OH, 45229, USA

    Stuart Goldstein

  4. Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    James Squires & George Mazariegos

Authors
  1. Armando Ganoza
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  2. Stuart Goldstein
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  3. James Squires
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  4. George Mazariegos
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Corresponding author

Correspondence to Armando Ganoza .

Editor information

Editors and Affiliations

  1. Jefferson Medical College, AI Dupont Hospital for Children Department of Surgery, Wilmington, Delaware, USA

    Stephen P. Dunn

  2. Liver & Intestine Transplantation, Seattle Children’s Hospital Liver & Intestine Transplantation, Seattle, Washington, USA

    Simon Horslen

Section Editor information

  1. Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, 555 University Avenue, M5G 1X8, Toronto, ON, Canada

    Vicky Lee Ng

  2. Pediatric Liver Care Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    John C. Bucuvalas

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Ganoza, A., Goldstein, S., Squires, J., Mazariegos, G. (2017). Peri-transplant Determinants of Outcome in Liver Transplantation. In: Dunn, S., Horslen, S. (eds) Solid Organ Transplantation in Infants and Children. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-08049-9_11-1

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  • DOI: https://doi.org/10.1007/978-3-319-08049-9_11-1

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