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Pediatric Nephrologist and the Infant or Child Before Kidney Transplantation

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Solid Organ Transplantation in Infants and Children

Part of the book series: Organ and Tissue Transplantation ((OTT))

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Abstract

Renal transplantation is the standard of care for the management of pediatric end-stage renal disease. Many infants, children, and adolescents require dialysis prior to transplant, and due to this therapeutic modality, transplant is considered elective. However, significant short-term and long-term morbidities are associated with dialysis, especially when necessary for prolonged periods. For this reason, preemptive renal transplant is desirable when it can be planned. Most chronic kidney disease and end-stage renal disease in pediatrics is due to congenital structural abnormalities, although the predominant causes of renal disease vary by age, geography, and ethnicity. A substantial proportion of pediatric renal disease has a known genetic cause. Effective management of chronic kidney disease, specifically its complications, can have a significant impact on outcomes and potentially delay the onset of end-stage renal disease.

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Authors and Affiliations

  1. Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA

    Christopher LaRosa

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  1. Christopher LaRosa
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Correspondence to Christopher LaRosa .

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Editors and Affiliations

  1. Department of Surgery, Jefferson Medical College, Wilmington, Delaware, USA

    Stephen P. Dunn

  2. Division of Gastroenterology, Seattle Children’s Hospital, Seattle, Washington, USA

    Simon Horslen

Section Editor information

  1. Diagnostic Referral Division, Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE, USA

    J Jeffrey Malatack

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LaRosa, C. (2018). Pediatric Nephrologist and the Infant or Child Before Kidney Transplantation. In: Dunn, S., Horslen, S. (eds) Solid Organ Transplantation in Infants and Children. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-07284-5_37

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  • DOI: https://doi.org/10.1007/978-3-319-07284-5_37

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-07283-8

  • Online ISBN: 978-3-319-07284-5

  • eBook Packages: MedicineReference Module Medicine

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