Peritransplant Determinants of Outcome in Liver Transplantation

  • Armando Ganoza
  • Stuart Goldstein
  • James Squires
  • George Mazariegos
Reference work entry
Part of the Organ and Tissue Transplantation book series (OTT)


Optimizing outcomes for children undergoing liver transplantation involves ongoing multidisciplinary assessment of medical morbidities unique to the underlying disease and specific patient population. In3reasing understanding of cardiopulmonary and renal factors as impacting posttransplant outcomes as well as high level of heterogeneity in patient diagnoses presenting for liver transplantation requires a dynamic approach in evaluation.

Technical expertise remains critical to early success of pediatric liver transplantation, and single center as well as network analysis (OPTN, SPLIT, others) has identified variation in outcomes as well as opportunities for improvement. Critical assessment and prophylaxis or intervention for infection and optimizing renal status in the early posttransplant period are critical as is timely management of surgical complications.


Liver transplant Early outcomes Surgical technique Medical and surgical complications 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Armando Ganoza
    • 1
  • Stuart Goldstein
    • 2
    • 3
  • James Squires
    • 1
  • George Mazariegos
    • 4
  1. 1.Children’s Hospital of PittsburghPittsburghUSA
  2. 2.Division of Nephrology and HypertensionCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  3. 3.Center for Acute Care NephrologyCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  4. 4.Hillman Center for Pediatric Transplantation, Children’s Hospital of Pittsburgh of UPMCPittsburghUSA

Section editors and affiliations

  • Vicky Lee Ng
    • 1
  • John C. Bucuvalas
    • 2
  1. 1.Division of Gastroenterology, Hepatology and NutritionThe Hospital for Sick ChildrenTorontoCanada
  2. 2.Pediatric Liver Care CenterCincinnati Children’s Hospital Medical CenterCincinnatiUSA

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