Skip to main content
SpringerLink
Log in
Book cover

Contemporary Liver Transplantation pp 617–626Cite as

Liver Transplantation in the Third Millennium in North America: The Strategy for Success

  • Reference work entry
  • First Online:

  • 1464 Accesses

Part of the book series: Organ and Tissue Transplantation ((OTT))

Abstract

Delivery of liver transplantation care has evolved, out of necessity, as programs have developed knowledge and expertise beyond the initial surgical challenges. This evolution has brought professionals from many different medical specialties together and has recognized the important contribution that other professions such as nursing, social work, pharmacy, psychology, and others that have resulted in a model for team-based care that today is applicable to other areas of medicine. In the third millennium, these teams will need to integrate further to become more efficient and cost conscious while they expand their attention to patient-centered quality of life outcomes in addition to the more traditional patient and graft survival results.

This is a preview of subscription content, log in via an institution.

References

  • A science odyssey: people and discoveries: first successful kidney transplant performed. PBS. Retrieved 25 Dec 2014

    Google Scholar 

  • Avolio AW, Halldorson JB, Lirosi MC, Lupo L, Nicolotti N, Agnes S (2013) D-MELD, a strong and accurate tool to guide donor-2-recipient matching. Ann Transplant 18:161–162

    Article  PubMed  Google Scholar 

  • Briceño J, Cruz-Ramírez M, Prieto M, Navasa M, Ortiz de Urbina J, Orti R, Gómez-Bravo MÁ, Otero A, Varo E, Tomé S, Clemente G, Bañares R, Bárcena R, Cuervas-Mons V, Solórzano G, Vinaixa C, Rubín A, Colmenero J, Valdivieso A, Ciria R, Hervás-Martínez C, de la Mata M (2014) Use of artificial intelligence as an innovative donor-recipient matching model for liver transplantation: results from a multicenter Spanish study. J Hepatol 61:1020–1028

    Article  PubMed  Google Scholar 

  • Buchanan P, Dzebisashvili N, Lentine KL, Axelrod DA, Schnitzler MA, Salvalaggio PR (2009) Liver transplantation cost in the model for end-stage liver disease era: looking beyond the transplant admission. Liver Transpl 15:1270–1277

    Article  PubMed  Google Scholar 

  • Calne RY, White DJ, Thiru S, Evans DB, McMaster P, Dunn DC, Craddock GN, Pentlow BD, Rolles K (1978) Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet 2(8104–5):1323–1327

    Article  CAS  PubMed  Google Scholar 

  • Calne RY, Rolles K, White DJ, Thiru S, Evans DB, McMaster P, Dunn DC, Craddock GN, Henderson RG, Aziz S, Lewis P (1979) Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers. Lancet 2(8151):1033–1036

    Article  CAS  PubMed  Google Scholar 

  • Cardoso FS, Bagshaw SM, Abraldes JG, Kneteman NM, Meeberg G, Fidalgo P, Karvellas CJ (2015) Comorbidities have a limited impact on post-transplant survival in carefully selected cirrhotic patients: a population-based cohort study. Ann Hepatol 14:505–514

    Article  PubMed  Google Scholar 

  • Chang Y, Gallon L, Jay C, Shetty K, Ho B, Levitsky J, Baker T, Ladner D, Friedewald J, Abecassis M, Hazen G, Skaro AI (2014) Comparative effectiveness of liver transplant strategies for end-stage liver disease patients on renal replacement therapy. Liver Transpl 20:1034–1044

    Article  PubMed  Google Scholar 

  • Elsayed FG, Sholkamy AA, Elshazli M, Elshafie M, Naguib M (2015) Comparison of different scoring systems in predicting short-term mortality after liver transplantation. Transplant Proc 47:1207–1210

    Article  CAS  PubMed  Google Scholar 

  • Federal Register, Vol 72, No 61 (Friday, March 30, 2007)

    Google Scholar 

  • Freeman RB (2007) Predicting the future? Liver Transpl 13:1503–1505

    Article  PubMed  Google Scholar 

  • Freeman RB, Weisner RH, Harper A, McDairmid SV, Lake J, Edwards EB, Merion R, Wolfe R, Turcotte J, Teperman L (2002) The new liver allocation system: moving towards evidence-based transplantation policy. Liver Transpl 8:851–858

    Article  PubMed  Google Scholar 

  • Habka D, Mann D, Landes R, Soto-Gutierrez A (2015) Future economics of liver transplantation: a 20-year cost modeling forecast and the prospect of bioengineering autologous liver grafts. PLoS One 10(7), e0131764

    Article  PubMed  PubMed Central  Google Scholar 

  • Jassal SV, Krahn MD, Naglie G, Zaltzman JS, Roscoe JM, Cole EH, Redelmeier DA (2003) Kidney transplantation in the elderly: a decision analysis. J Am Soc Nephrol 14:187–196

    Article  PubMed  Google Scholar 

  • Kanter KR, McBride LR, Pennington DG, Swartz MT, Ruzevich SA, Miller LW, Willman VL (1988) Bridging to cardiac transplantation with pulsatile ventricular assist devices. Ann Thorac Surg 46:134–140

    Article  CAS  PubMed  Google Scholar 

  • Kensinger CD, Dageforde LA, Moore DE (2013) Can donors with high donor risk indices be used cost-effectively in liver transplantation in US Transplant Centers? Transpl Int 26:1063–1069

    Article  PubMed  Google Scholar 

  • Li M, Dick A, Montenovo M, Horslen S, Hansen R (2015) Cost-effectiveness of liver transplantation in methylmalonic and propionic acidemias. Liver Transpl 21(9):1208–18. doi:10.1002/lt.24173

    Article  PubMed  Google Scholar 

  • Lim KC, Wang VW, Siddiqui FJ, Shi L, Chan ES, Oh HC, Tan SB, Chow PK (2015) Cost-effectiveness analysis of liver resection versus transplantation for early hepatocellular carcinoma within the Milan criteria. Hepatology 61:227–237

    Article  PubMed  Google Scholar 

  • Mathis AS (2015) Managed care implications of improving long-term outcomes in organ transplantation. Am J Manag Care 21(1 Suppl):s24–s30

    PubMed  Google Scholar 

  • NOTA; P.L. 98–507

    Google Scholar 

  • Owens GM (2015) Revolutionizing treatment outcomes in hepatitis c: managed care implications and considerations-the new and evolving standards of care. Am J Manag Care 21(5 Suppl):s97–s105

    PubMed  Google Scholar 

  • Pan HC, Jenq CC, Lee WC, Tsai MH, Fan PC, Chang CH, Chang MY, Tian YC, Hung CC, Fang JT, Yang CW, Chen YC (2014) Scoring systems for predicting mortality after liver transplantation. PLoS One 9(9):e107138

    Article  PubMed  PubMed Central  Google Scholar 

  • Parker R, Armstrong MJ, Bruns T, Hodson J, Rowe IA, Corbett CD, Reuken PA, Gunson BK, Houlihan DD, Stephenson B, Malessa C, Lester W, Ferguson JW (2014) Reticulocyte count and hemoglobin concentration predict survival in candidates for liver transplantation. Transplantation 97:463–469

    Article  CAS  PubMed  Google Scholar 

  • Reichert B, Becker T, Weismüller TJ, Kleine M, Zachau L, Johanning K, Lehner F, Klempnauer J, Schrem H (2012) Value of the preoperative SOFT-score, P-SOFT-score, SALT-score and lab MELD-score for the prediction of short-term patient and graft survival of high-risk liver transplant recipients with a pre-transplant lab MELD-score ≥30. Ann Transplant 17:11–17

    PubMed  Google Scholar 

  • Rosselli D, Rueda JD, Diaz CE (2015) Cost-effectiveness of kidney transplantation compared with chronic dialysis in end-stage renal disease. Saudi J Kidney Dis Transpl 26:733–738

    Article  PubMed  Google Scholar 

  • Salvalaggio PR, Dzebisashvili N, MacLeod KE, Lentine KL, Gheorghian A, Schnitzler MA, Hohmann S, Segev DL, Gentry SE, Axelrod DA (2011) The interaction among donor characteristics, severity of liver disease, and the cost of liver transplantation. Liver Transpl 17:233–42

    Article  PubMed  PubMed Central  Google Scholar 

  • Schwartz and Dameshek 1960, J Clin Invest. Jun; 39(6): 952–958.

    Google Scholar 

  • Schnitzler MA, Lentine KL, Burroughs TE (2005) The cost effectiveness of deceased organ donation. Transplantation 80:1636–37

    Article  PubMed  Google Scholar 

  • see http://optn.transplant.hrsa.gov/governance/bylaws/; Accessed 14 April 2015

  • see http://www.srtr.org/local_stats.aspx; Accessed 14 April 2015

  • See http://xynmanagement.com/solutions/srtr-performance/xynplot/; Accessed 14 April 2015

  • Shah M, Younossi ZM (2015) Revolutionizing treatment outcomes in hepatitis C: managed care implications and considerations-diagnosis and management. Am J Manag Care 21(5 Suppl):s86–96

    PubMed  Google Scholar 

  • Soárez PC, Lara AN, Sartori AM, Abdala E, Haddad LB, D'Albuquerque LA, Novaes HM (2015) Healthcare resource utilization and costs of outpatient follow-up after liver transplantation in a university hospital in São Paulo Brazil: cost description study. Sao Paulo Med J 133:171–8

    Article  PubMed  Google Scholar 

  • Stahl CC, Wima K, Hanseman DJ, Hoehn RS, Ertel A, Midura EF, Hohmann SF, Paquette IM, Shah SA, Abbott DE (2015) Organ quality metrics are a poor predictor of costs and resource utilization in deceased donor kidney transplantation. Surgery. doi:10.1016/j.surg.2015.05.014 (Epub ahead of print)

    Google Scholar 

  • Starzl TE, Marchioro TL, Huntley RT, Rifkind D, Rowlands DT, Dickinson TC, Waddell WR (1964) Experimental and clinical homotransplantation of the liver. Ann N Y Acad Sci 120:739–65

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Talwalkar JA (2014) Health services and policy research in hepatology. Curr Opin Gastroenterol 30:272–8

    Article  PubMed  Google Scholar 

  • Weeks P, Blais I (2011) Understanding the episode of care for transplant patients. BMC Health Serv Res 11(Suppl 1):A23

    Article  PubMed Central  Google Scholar 

  • Younis M, Jabr S, Al-Khatib A, Forgione D, Hartmann M, Kisa A (2015) A cost analysis of kidney replacement therapy options in Palestine. Inquiry 11:52. doi:10.1177/0046958015573494

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, Dartmouth Hitchcock Medical Center, Geisel School of Medicine, 1 Medical Center Drive, Lebanon, NH, 03756, USA

    Richard B. Freeman

Authors
  1. Richard B. Freeman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard B. Freeman .

Editor information

Editors and Affiliations

  1. Nicoletti Family Professor of Transplant Surgery, Director, Jefferson Transplant Institute, Director, Division of Transplantation, Surgical Director, Kimmel Cancer Center – Jefferson Liver Tumor Center, Sidney Kimmel Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

    Cataldo Doria

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this entry

Cite this entry

Freeman, R.B. (2017). Liver Transplantation in the Third Millennium in North America: The Strategy for Success. In: Doria, C. (eds) Contemporary Liver Transplantation. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-07209-8_38

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-07209-8_38

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-07208-1

  • Online ISBN: 978-3-319-07209-8

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation