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Interventional Radiology for the Pre-transplant Patient

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Book cover Contemporary Liver Transplantation

Part of the book series: Organ and Tissue Transplantation ((OTT))

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Abstract

Interventional radiology is essential to the multidisciplinary liver transplant program. The goal of the interventional radiologist is to decrease the dropout rate from the transplant waiting list. Decreasing the dropout rate is accomplished twofold: (1) treating sequelae of portal hypertension and (2) treating hepatocellular carcinoma. The interventional radiologist has the knowledge base and skill set to treat sequelae of severe portal hypertension by creating transjugular intrahepatic portosystemic shunts (TIPS), thereby treating life-threatening hemorrhage and/or improving the patients’ quality of life. In patients with hepatocellular carcinoma, the interventional radiologist performs palliative therapies in order to maintain the disease within size and number criteria required for transplantation. In patients with hepatocellular carcinoma beyond transplant criteria, the same palliative therapies are performed to potentially downstage cancer so that patients become eligible for transplant candidacy. Numerous prospective and retrospective clinical trials, which will be discussed in this chapter, have shown the efficacy of procedures performed by interventional radiologists. Through a discussion of these procedures, an understanding of the critical role of interventional radiology for the pretransplant patient can be made.

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  1. Thomas Jefferson University Hospital, Philadelphia, PA, USA

    Susan Shamimi-Noori

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Correspondence to Susan Shamimi-Noori .

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  1. Nicoletti Family Professor of Transplant Surgery, Director, Jefferson Transplant Institute, Director, Division of Transplantation, Surgical Director, Kimmel Cancer Center – Jefferson Liver Tumor Center, Sidney Kimmel Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

    Cataldo Doria

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Shamimi-Noori, S. (2017). Interventional Radiology for the Pre-transplant Patient. In: Doria, C. (eds) Contemporary Liver Transplantation. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-07209-8_23

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