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Medical Evaluation of the Diabetic Patient for Pancreas Transplant

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Contemporary Pancreas and Small Bowel Transplantation

Part of the book series: Organ and Tissue Transplantation ((OTT))

Abstract

Pancreas transplantation has the ability to restore normoglycemia in patients with insulin-dependent diabetes mellitus. As a result, it can potentially improve the quality of life and reduce the deleterious effects of the secondary complications of diabetes mellitus. Pancreas transplant surgery has a significant risk of surgical and infectious complications, although these risks are decreasing as more experience in the field is gained. A long-term mortality benefit for pancreas transplantation has not been shown and the selection of the potential pancreas transplant candidate must be strict. Risk factors for pancreas transplantation include older age, cardiovascular disease, and peripheral vascular disease. There are three different options for pancreas transplantation: (1) pancreas transplantation alone, (2) pancreas after kidney transplantation, and (3) simultaneous pancreas and kidney transplantation. Pancreas transplant alone is reserved for the patient who has adequate kidney function. The decision to perform pancreas after kidney transplantation or simultaneous pancreas and kidney transplantation should be made on an individual basis. Both options are superior to deceased donor kidney transplantation alone but do not appear to have a survival benefit compared to living donor kidney transplantation alone.

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Author information

Authors and Affiliations

  1. Saint Barnabas Medical Center, Livingston, NJ, USA

    Anup M. Patel

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  1. Anup M. Patel
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Correspondence to Anup M. Patel .

Editor information

Editors and Affiliations

  1. Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA

    Ashesh Piyush Shah

  2. Capital Health Cancer Center, Pennington, NJ, USA

    Cataldo Doria

  3. Porter Adventist Hosptial, Denver, CO, USA

    James W. Lim

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Patel, A.M. (2019). Medical Evaluation of the Diabetic Patient for Pancreas Transplant. In: Shah, A., Doria, C., Lim, J. (eds) Contemporary Pancreas and Small Bowel Transplantation . Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-05257-1_2011

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  • DOI: https://doi.org/10.1007/978-3-319-05257-1_2011

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-05256-4

  • Online ISBN: 978-3-319-05257-1

  • eBook Packages: MedicineReference Module Medicine

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