Sclerosing Adenosis of the Prostate
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It is incidentally found in about 2% of TURP specimens.
Usually in the age of benign prostatic hyperplasia.
Small microacini, solid clusters, cords, and single cells are seen in a background of cellular spindle cell stroma. Glands are lined by cells with clear or amphophilic cytoplasm and nuclei without prominent nucleoli. Sclerosing adenosis with significant cytological atypia mimics adenocarcinoma. Presence of an intact basal cell layer allows to distinguish it from PCa (Fig. 1) (Berney et al. 2007; (Cheng and Bostwick 2010; Collina et al. 1992; Grignon et al. 1992;...
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