Synonyms
Granular cells myoblastoma (obsolete)
Clinical Features
Incidence
Granular cell tumor is quite rare in the male genitourinary tract. Indeed, 17 cases are reported in the bladder and < 20 cases in male genitalia (Bedir et al. 2017; Pu et al. 2015).
Age
The lesion can occur at all ages (bladder 14–70 years, external male genitalia 6–89) (Cheville and Folpe 2016; Richmond et al. 2016; Pu et al. 2015).
Sex
In the bladder, it occurs in both males and females, while in the external genitalia occurs only in males (Cheville and Folpe 2016; Bedir et al. 2017; Pu et al. 2015; Richmond et al. 2016).
Site
The tumor can occur in the bladder, urethra, external genital tract (penis and scrotum), and...
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Bedir, R., Yılmaz, R., Özdemir, O., & Uzun, H. (2017). Granular cell tumor of the urinary bladder. Turkish Journal of Urology, 43(3), 383–385.
Cheville, J., & Folpe, A. (2016). Tumours of the genitourinary tract in WHO classification of tumours of the urinary system and male genital organs (4th edn, pp. 122–127). IARC, Lyon.
Fanburg-Smith, J. C., Meis-Kindblom, J. M., Fante, R., & Kindblom, L. G. (1998). Malignant granular cell tumor of soft tissue: Diagnostic criteria and clinicopathologic correlation. The American Journal of Surgical Pathology, 22(7), 779–794.
Gurzu, S., Ciortea, D., Tamasi, A., Golea, M., Bodi, A., Sahlean, D. I., Kovecsi, A., & Jung, I. (2015). The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin. Archives of Dermatological Research, 307(2), 151–157.
Pu, C. X., Gao, L., Bai, Y. J., & Han, P. (2015). Granular cell tumor of the urethra: A case report and literature review. Asian Journal of Andrology, 18(6), 946–948.
Richmond, A. M., La Rosa, F. G., & Said, S. (2016). Granular cell tumor presenting in the scrotum of a pediatric patient: A case report and review of the literature. Journal of Medical Case Reports, 10(1), 161.
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Taverna, C., Franchi, A. (2020). Granular Cell Tumor, Genitourinary Tract. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_5007
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DOI: https://doi.org/10.1007/978-3-030-41894-6_5007
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