Definition
Lymphangioma is a benign proliferation of lymphatic vessels.
Clinical Features
Incidence
Lymphangiomas of the urogenital tract are exceptionally rare.
Age
Lymphangiomas are detected mainly in children and young adults.
Sex
No gender predilection is reported.
Site
A superficial microcystic variant (lymphangioma circumscriptum) and a deep macrocystic variant (cavernous lymphangioma) can be recognized. Lymphangioma circumscriptum may exceptionally occur in the penoscrotal region, while cystic lymphangioma may arise in the kidney and urinary tract, including the urethra and the bladder.
Treatment
The standard treatment is radical surgical resection.
Outcome
No recurrence is usually noted after complete removal of the lesion.
Macroscopy
Lymphangioma circumscriptum presents with multiple, grouped, translucent vesicles that may sometimes become pink or red because of hemorrhage from adjacent capillaries. A hyperkeratotic, verrucous surface may develop in older lesions. Deep...
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Daklan, S., & Daryakar, A. (2018). Lymphangioma circumscriptum of glans penis: A report of two cases. Dermatology Online Journal, 24(8). pii: 13030/qt9pr342qv.
Laurent, F., Joullie, M., Biset, J. M., Simon, J. M., & Drouillard, J. (1991). Cystic lymphangioma of the kidney: A rare cause of multiloculated renal masses. European Journal of Radiology, 12, 67–68.
Macki, M., Anand, S. K., Jaratli, H., & Dabaja, A. A. (2019). Penile Lymphangioma: Review of the literature with a case presentation. Basic and Clinical Andrology, 29, 1.
Mehta, V., Ananthanarayanan, V., Antic, T., Krausz, T., Milner, J., Venkataraman, G., & Picken, M. M. (2012). Primary benign vascular tumors and tumorlike lesions of the kidney: A clinicopathologic analysis of 15 cases. Virchows Archiv, 461, 669–676.
Niu, Z. B., Yang, Y., Hou, Y., Chen, H., Liu, X., & Wang, C. L. (2010). Lymphangioma of bladder. Urology, 76, 955–957.
Topaloglu, H., Karakoyunlu, N., Ozok, U., Dilli, A., Onder, E., Sagnak, L., & Ersoy, H. (2013). Lymphangioma of pyeloureteral junction: An extremely rare case. Urologia Internationalis, 90, 243–245.
Wyler, S. F., Bachmann, A., Singer, G., Gasser, T. C., & Sulser, T. (2004). First case of lymphangioma of the bladder in an adult. Urologia Internationalis, 73, 374–375.
Zapzalka, D. M., Krishnamurti, L., Manivel, J. C., & DiSandro, M. J. (2002). Lymphangioma of the renal capsule. The Journal of Urology, 168, 220.
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Franchi, A. (2020). Lymphangioma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_5005
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DOI: https://doi.org/10.1007/978-3-030-41894-6_5005
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