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Angiosarcoma multiplex; Granuloma multiplex hemorrhagicum; Idiopathic multiple pigmented sarcoma of the skin
Kaposi sarcoma (KS), first described by Moritz Kaposi in 1872, is an angioproliferative disorder of endothelial origin, which can be considered as a low grade, locally aggressive tumor or as a tumor-like lesion. It is strictly associated to human herpesvirus 8 (HHV-8) infection (Micali et al. 2003).
Kaposi sarcoma is divided into four clinical subtypes: classical indolent, endemic African, iatrogenic, and AIDS-associated. The site of the lesion can vary from lower extremities in the classical form to lymph node involvement in the endemic type and to a more generalized localization in the two latter forms. In each subtype the involvement of external genitalia is very rare and when it occurs is usually related to HIV/AIDS-associated immunocompromised status. The cases arising in HIV-negative patients are exceedingly rare, with 19...
References and Further Reading
- Mentzel, T., Knuutila, S., & Lamovec, J. (2013). Kaposi sarcoma. In C. D. M. Fletcher, J. A. C. Bridge, P. Hogendoorn, & F. Mertens (Eds.), WHO classification of tumours of soft tissue and bone (pp. 151–153). Lyon: IARC.Google Scholar
- Weiss, S. W. (2001). Enzinger and Weiss’s soft tissue tumors. St. Louis: Mosby.Google Scholar