Synonyms
Verrucous carcinoma
Definition
Low-grade squamous cell carcinoma without atypia.
Clinical Features
Incidence
Rare tumor represents 3% of the squamous tumors of the bladder. It is mainly reported in patients with schistosomiasis (Mahran and el-Baz 1993). One case of verrucous carcinoma has been described in a patient with a long-standing condyloma acuminatum (Walther et al. 1986).
Age
Few reported cases in 40–50-year-old patients.
Sex
Female predominance as in the squamous cell carcinoma associated with schistosomiasis.
Site
Rare urogenital tract case examples have been reported in the bladder. It may also occur in a bladder diverticulum (Holck and Jørgensen 1983; Chiang et al. 1991).
Treatment
Cystectomy allows the right diagnosis and is also therapeutic.
Outcome
It is associated with a very low risk of progression (Mahran and el-Baz 1993). Lymph-node metastases have been not reported (El-Sebair et al. 1974).
Macroscopy
Grossly, it presents as a warty tumor mass of variable...
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Chiang, P. H., Chou, Y. H., Chiang, C. P., et al. (1991). Verrucous carcinoma of vesical diverticulum. British Journal of Urology, 68, 320–321.
El-Sebair, I., Sherif, M., El-Bolkainy, M. N., et al. (1974). Verrucose squamous carcinoma of the bladder. Urology, 4, 407–410.
Holck, S., & Jørgensen, L. (1983). Verrucous carcinoma of urinary bladder. Urology, 22, 435–437.
Mahran, M. R., & el-Baz, M. (1993). Verrucous carcinoma of the bilharzial bladder. Impact of invasiveness on survival. Scandinavian Journal of Urology and Nephrology, 27(2), 189–192.
Walther, M., O’Brien, D. P., III, & Birch, H. W. (1986). Condyloma acuminate and verrucous carcinoma of the bladder: Case report and literature review. The Journal of Urology, 135, 362–365.
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Raspollini, M.R., Lopez-Beltran, A. (2020). Urinary Tract Verrucous Carcinoma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4976
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4976
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