Definition
It is a benign tumor of the epithelium of the rete testis encompassing a spectrum from closely packed tubules to papillary and/or cystic proliferations or solid tubules resembling a Sertoli cell tumor (sertoliform cystadenoma).
Clinical Features
Incidence
Extremely rare.
Age
Mean age at presentation is 25 years, but the range is between second to eight decade of life.
Site
The lesion is centered in the hilum of the testis.
Treatment
Excision and follow up is adequate.
Outcome
All the reported cases are benign.
Macroscopy
The tumors are solid to cystic, well-circumscribed masses centered in the hilum of the testis.
Microscopy
It is a cystic, sometimes papillary lesion lined with cuboidal cells without atypia or mitotic figures. The lesion is centered in the hilum of the testis and transition from normal rete epithelium is helpful in supporting the diagnosis. The lining cells are cuboidal to columnar and stratified, but lack mitotic figures and atypia. Few cases of sertoliform...
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References and Further Reading
Amin, M. B. (2005). Selected other problematic testicular and paratesticular lesions: Rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors. Modern Pathology, 18(Suppl 2), S131–S145.
Michael, H., & Srigley, J. (2013). Pathology of the paratesticular region. In Urological pathology (1st ed., pp. 804–854). Philadelphia: Lippincott Williams and Wilkins.
Paluru, S., Ulbright, T. M., Amin, M., et al. (2018). The morphologic spectrum of Sertoliform cystadenoma of the rete testis: A series of 15 cases. The American Journal of Surgical Pathology, 42(2), 141–149.
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Colecchia, M., Bertolotti, A. (2020). Testis Collecting Duct and Rete Testis Adenoma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4960
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4960
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