Clinical Features
Incidence
Four cases have been reported.
Age
The patients were aged 26, 54, 61, and 69 years.
Sex
Male.
Site
Seminal vesicles.
Treatment
Early diagnosis and treatment are crucial for primary squamous cell carcinoma of the seminal vesicle.
Outcome
The young patient received complete resection of the tumor; 28 months after surgery pelvic metastases were identified. In one patient, rectal metastasis occurred 7 months after resection, despite chemotherapy, leading to death. Another patient had no evidence of disease after external beam radiation, with no recurrence 2.5 years later (Tabata et al. 2002; Tang et al. 2016; Wang et al. 2013; Yanagisawa et al. 2002).
Macroscopy
The tumors were septated cystic and solid masses measuring 4–11 cm.
Microscopy
Keratinizing squamous cell carcinoma is observed along with...
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References and Further Reading
Tabata, K., Irie, A., Ishii, D., Yanagisawa, N., Iwamura, M., & Baba, S. (2002). Primary squamous cell carcinoma of the seminal vesicle. Urology, 59, 445.
Tang, K., Sun, F. A., Tian, Y., Xiao, Y., Sun, C., & Wang, P. (2016). Primary squamous cell carcinoma of the seminal vesicle: A case report. Molecular and Clinical Oncology, 4(3), 416–418.
Wang, J., Yue, X., Zhao, R., Cheng, B., Wazir, R., & Wang, K. (2013). Primary squamous cell carcinoma of seminal vesicle: An extremely rare case report with literature review. International Urology and Nephrology, 45, 135–138.
Yanagisawa, N., Saegusa, M., Yoshida, T., & Okayasu, I. (2002). Squamous cell carcinoma arising from a seminal vesicular cyst: Possible relationship between chronic inflammation and tumor development. Pathology International, 52(3), 249–253.
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Cimadamore, A., Montironi, R. (2020). Seminal Vesicle Squamous Cell Carcinoma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4937
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4937
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