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Seminal Vesicle Adenocarcinoma

  • Reference work entry
  • First Online:
Uropathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 8 Accesses

Definition

Primary seminal vesicle adenocarcinoma (PSVA) is an extremely rare malignancy ranging from well-differentiated adenocarcinoma forming papillary structures to poorly differentiated histology. PSVA should be localized exclusively or mainly to the seminal vesicle and a secondary origin from prostate, colon, or bladder should be excluded (Campobasso et al. 2012; Lote et al. 2013).

Clinical Features

  • Incidence

    Only approximately 60 cases have been reported to date.

  • Age

    The age of onset is quite varied, ranging from 19 to 90 years old.

  • Sex

    Male.

  • Site

    Seminal vesicle.

  • Treatment

    Currently, there is no established guideline for the treatment of seminal vesicle adenocarcinoma. Complete resection appears to offer the best chance for therapy but hormonal manipulation and radiotherapy seem to be effective as adjuvant treatment modalities (Thyavihally et al. 2007; Yin and Jiang 2018).

  • Outcome

    Prognosis is poor, with survival usually <3 years (Thyavihally et al. 2007; Yin and Jiang 2018).

    ...

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References and Further Reading

  • Campobasso, D., Fornia, S., Ferretti, S., et al. (2012). Primary bilateral seminal vesicle carcinoma: Description of a case and literature review. International Journal of Surgical Pathology, 20, 633–635.

    Article  PubMed  Google Scholar 

  • Lote, H., Mannion, E., Cook, T., et al. (2013). Adenocarcinoma of the seminal vesicles complicated by antineutrophil cytoplasmic antibody vasculitis: A case report and review of the literature. Journal of Medical Case Reports, 7, 59.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ohmori, T., Okada, K., Tabei, R., et al. (1994). CA125-producing adenocarcinoma of the seminal vesicle. Pathology International, 44, 333–337.

    Article  CAS  PubMed  Google Scholar 

  • Ormsby, A. H., Haskell, R., Jones, D., et al. (2000). Primary seminal vesicle carcinoma: A immunohistochemical analysis of four cases. Modern Pathology, 13, 46–51.

    Article  CAS  PubMed  Google Scholar 

  • Thyavihally, Y. B., Tongaonkar, H. B., Gupta, S., et al. (2007). Primary seminal vesicle adenocarcinoma presenting as isolated metastasis to penis responding to chemotherapy and hormonal therapy. Urology, 69, 778e1–778e3.

    Article  Google Scholar 

  • Yin, T., & Jiang, Y. (2018). A 5-year follow-up of primary seminal vesicle adenocarcinoma: A case report. Medicine (Baltimore), 97(41), e12600.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region (Ancona), United Hospitals Ancona, Ancona, Italy

    Alessia Cimadamore & Rodolfo Montironi

  2. Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA

    Liang Cheng

Authors
  1. Alessia Cimadamore
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  2. Liang Cheng
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  3. Rodolfo Montironi
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Corresponding author

Correspondence to Rodolfo Montironi .

Editor information

Editors and Affiliations

  1. Histopathology and Molecular Diagnostics, University Hospital Careggi, Florence, Italy

    Maria Rosaria Raspollini

  2. Pathology Service, Champalimaud Clinical Center, Lisbon, Portugal

    Antonio Lopez-Beltran

  3. Unit of Anatomic Pathology, Department of Surgery, Cordoba University Medical School, Cordoba, Spain

    Antonio Lopez-Beltran

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Cite this entry

Cimadamore, A., Cheng, L., Montironi, R. (2020). Seminal Vesicle Adenocarcinoma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4935

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  • DOI: https://doi.org/10.1007/978-3-030-41894-6_4935

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-41893-9

  • Online ISBN: 978-3-030-41894-6

  • eBook Packages: MedicineReference Module Medicine

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