Seminal Vesicle Adenocarcinoma
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Primary seminal vesicle adenocarcinoma (PSVA) is an extremely rare malignancy ranging from well-differentiated adenocarcinoma forming papillary structures to poorly differentiated histology. PSVA should be localized exclusively or mainly to the seminal vesicle and a secondary origin from prostate, colon, or bladder should be excluded (Campobasso et al. 2012; Lote et al. 2013).
Only approximately 60 cases have been reported to date.
The age of onset is quite varied, ranging from 19 to 90 years old.
Currently, there is no established guideline for the treatment of seminal vesicle adenocarcinoma. Complete resection appears to offer the best chance for therapy but hormonal manipulation and radiotherapy seem to be effective as adjuvant treatment modalities (Thyavihally et al. 2007; Yin and Jiang 2018).