2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Scrotal Fat Necrosis

  • Maria Rosaria RaspolliniEmail author
  • Antonio Lopez-Beltran
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4934


Fat necrosis of the scrotum


Firm nodules in the lower part of the scrotal wall.

Clinical Features

  • Incidence

    It occurs in stout or fat boys before puberty. It represents 1% of the acute pediatric lesion arising in the scrotum (Murphy et al. 2006).

  • Age

    It affects children and adolescents.

  • Sex


  • Site

    Scrotum: usually the lesions are bilateral and symmetrical (Peterson et al. 1976). The testis is not involved.

  • Treatment

    Most cases are conservatively managed. When diagnosis is not clear clinically, lumpectomy is advocated.

  • Outcome



Ill-defined gray-yellow nodules limited to the scrotal wall.


Histologically, the lesions show fat necrosis with inflammation (Ong and Solomon 1973).

Differential Diagnosis

Biopsies in this setting are exceptional; the diagnosis in the majority of the cases is clinically done (history of cold exposure prior to the onset of scrotal pain and ultrasound evaluation). Differential diagnosis must be done with fat tumors...

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References and Further Reading

  1. Murphy, F. L., Fletcher, L., & Pease, P. (2006). Early scrotal exploration in all cases is the investigation and intervention of choice in the acute paediatric scrotum. Pediatric Surgery International, 22, 413–416.PubMedCrossRefGoogle Scholar
  2. Ong, T. H., & Solomon, J. R. (1973). Fat necrosis of the scrotum. Journal of Pediatric Surgery, 8, 919–924.PubMedCrossRefGoogle Scholar
  3. Peterson, L. J., Whitlock, N. W., Odom, R. B., et al. (1976). Bilateral fat necrosis of the scrotum. The Journal of Urology, 116, 825–826.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Maria Rosaria Raspollini
    • 1
    Email author
  • Antonio Lopez-Beltran
    • 2
    • 3
  1. 1.Histopathology and Molecular DiagnosticsUniversity Hospital CareggiFlorenceItaly
  2. 2.Pathology ServiceChampalimaud Clinical CenterLisbonPortugal
  3. 3.Unit of Anatomic Pathology, Department of SurgeryCordoba University Medical SchoolCordobaSpain