Sclerosing Lipogranuloma

Synonyms

Eosinophilic sclerosing lipogranuloma; Paraffinoma

Definition

Sclerosing lipogranuloma (SLG) is a rare, reactive lesion, with both primary idiopathic and secondary traumatic origin, composed by granulomatous inflammation consequent to injury of the adipose tissue.

Clinical Features

• Incidence

  Sclerosing lipogranuloma is a rare lesion, with most cases reported as secondary to foreign material injection of oil-based substances in the external genitalia. Idiopathic cases are exceeding rare (Ricchiuti et al. 2012; Ohtsuki et al., 2007; Foxton et al., 2011; Singam et al. 2010).

• Age

  Sclerosing lipogranuloma can occur at all ages. In particular, if the lesion is secondary to injection of foreign substances, it is more likely to occur in young adults (Ricchiuti et al. 2012; Ohtsuki et al. 2007; Foxton et al. 2011; Singam et al. 2010).

• Sex

  The lesion typically occurs in male genital region.

• Site

  Most common sites of occurrence comprise perineal region and scrotum, but sclerosing...