Uropathology

2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Ossifying Renal Tumor of Infancy

  • Anna Caliò
  • Diego Segala
  • Guido MartignoniEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4865
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Definition

Ossifying renal tumor of infancy is an intracalyceal mass composed of osteoid trabeculae, osteoblast-like cells, and a spindle cell component.

Clinical Features

  • Incidence

    Ossifying renal tumor of infancy is an extremely rare neoplasm, there few reported cases (Hu et al. 2013).

  • Age

    Usually diagnosed in the first 2 years of life

  • Sex

    It affects predominantly in boys (6:1 male-to-female ratio).

  • Site

    There is no site predilection.

  • Treatment

    The treatment modalities for ossifying renal tumors of infancy are either nephrectomy or partial nephrectomy depending on the size and location of the tumor.

  • Outcome

    Ossifying renal tumors of infancy are believed to be benign in nature, as there have been no reports of progression or malignant disease.

Macroscopy

It is grossly well-circumscribed mass.

Microscopy

Ossifying renal tumor of infancy has three major components: an osteoid core, osteoblastic cells within and at the periphery of the osteoid, and bland spindle cells. The latter...

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References and Further Reading

  1. Hu, J., Wu, Y., Qi, J., Zhang, C., & Lv, F. (2013). Ossifying renal tumor of infancy (ORTI): A case report and review of the literature. Journal of Pediatric Surgery, 48, e37–e40.CrossRefGoogle Scholar
  2. Liu, J., Guzman, M. A., Pawel, B. R., et al. (2013). Clonal trisomy 4 cells detected in the ossifying renal tumor of infancy: Study of 3 cases. Modern Pathology, 26, 275–281.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Diagnostic and Public Health, Section of PathologyUniversity of VeronaVeronaItaly
  2. 2.Department of PathologyPederzoli HospitalPeschiera del GardaItaly