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Nephroblastic tumors include nephroblastoma, the most common, and cystic partially differentiated nephroblastoma.
Nephroblastoma is a malignant tumor which comprises more than 85% of pediatric renal tumors and 5% of childhood cancers.
It is usually found in children 2–4 years old, it is relatively uncommon in the first 6 months of life and in children older than 6 years, whereas it is rare in the neonatal period. Nephroblastoma rarely occurs in adults.
There is no gender predilection.
Five percent of the tumors are multicentric and bilateral.
Tumor resection followed by chemotherapy or adjuvant chemotherapy and surgical treatment are the two different protocols of therapy.
Despite the different managements, the overall survival currently is more than 90%.
The associations with cryptorchidism, hypospadias, other genital anomalies, hemihypertrophy, and aniridia are well-recognized and described in...