2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran


  • Francesca PortelliEmail author
  • Chiara Trambaiolo Antonelli
  • Vincenzo De Giorgi
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4859


Genital nevocytic nevus; Nevus of the genital tract


Nevus is a benign proliferation of melanocytes.

Clinical Features

  • Incidence

    Bladder is an exceedingly rare location, with only one case, namely, a cellular blue nevus, reported (Kim et al. 2012). In the prostate 28 cases of blue nevus, the most frequently reported pigmented prostatic lesion, have been described. The incidence of blue nevi in consecutive surgical prostatic specimens and autopsy has been 0.05% and 0.6%, respectively (Dailey and Hameed 2011).

    Nevi on male genitalia are much less frequently encountered than in women.

  • Age

    In the bladder the case of cellular blue nevus was described in a 72-year-old woman with a history of breast cancer (Kim et al. 2012).

    The age at the detection of the reported cases of blue nevi of prostate ranged from 20 to 81 years (Dailey and Hameed 2011).

    Genital nevi typically occur in young adults.

  • Sex

    Not applicable

  • Site

    In the urogenital tract nevi have been described in the...

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References and Further Reading

  1. Ahn, C. S., Guerra, A., & Sangueza, O. P. (2016). Melanocytic nevi of special sites. American Journal of Dermatopathology, 38, 867–881.CrossRefGoogle Scholar
  2. Cengiz, F. P., Emiroglu, N., & Wellenhof, R. H. (2015). Dermoscopic and clinical features of pigmented skin lesions of the genital area. Anais Brasileiros de Dermatologia, 90, 178–183.CrossRefGoogle Scholar
  3. Dailey, V. L., & Hameed, O. (2011). Blue nevus of the prostate. Archives of Pathology & Laboratory Medicine, 135, 799–802.Google Scholar
  4. Kim, J., McCarthy, S. W., Thompson, J. F., Pupo, G. M., Vonthethoff, L., Nash, P., Mann, G. J., & Scolyer, R. A. (2012). Cellular blue nevus involving the urinary bladder. Pathology, 44, 664–668.CrossRefGoogle Scholar
  5. Nguyen, L. P., Emley, A., Wajapeyee, N., Green, M. R., & Mahalingam, M. (2010). BRAF V600E mutation and the tumour suppressor IGFBP7 in atypical genital naevi. British Journal of Dermatology, 162, 677–680.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Francesca Portelli
    • 1
    Email author
  • Chiara Trambaiolo Antonelli
    • 2
  • Vincenzo De Giorgi
    • 3
  1. 1.Section of Anatomical Pathology, Department of Health SciencesAzienda Ospedaliero-Universitaria Careggi, University of FlorenceFlorenceItaly
  2. 2.Departments of Anatomical Pathology and of Oncology, Ospedale Policlinico San MartinoUniversity of GenoaGenoaItaly
  3. 3.Dermatologic ClinicUniversity of FlorenceFlorenceItaly