Synonyms
Genital nevocytic nevus; Nevus of the genital tract
Definition
Nevus is a benign proliferation of melanocytes.
Clinical Features
Incidence
Bladder is an exceedingly rare location, with only one case, namely, a cellular blue nevus, reported (Kim et al. 2012). In the prostate 28 cases of blue nevus, the most frequently reported pigmented prostatic lesion, have been described. The incidence of blue nevi in consecutive surgical prostatic specimens and autopsy has been 0.05% and 0.6%, respectively (Dailey and Hameed 2011).
Nevi on male genitalia are much less frequently encountered than in women.
Age
In the bladder the case of cellular blue nevus was described in a 72-year-old woman with a history of breast cancer (Kim et al. 2012).
The age at the detection of the reported cases of blue nevi of prostate ranged from 20 to 81 years (Dailey and Hameed 2011).
Genital nevi typically occur in young adults.
Sex
Not applicable
Site
In the urogenital tract nevi have been described in the...
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Ahn, C. S., Guerra, A., & Sangueza, O. P. (2016). Melanocytic nevi of special sites. American Journal of Dermatopathology, 38, 867–881.
Cengiz, F. P., Emiroglu, N., & Wellenhof, R. H. (2015). Dermoscopic and clinical features of pigmented skin lesions of the genital area. Anais Brasileiros de Dermatologia, 90, 178–183.
Dailey, V. L., & Hameed, O. (2011). Blue nevus of the prostate. Archives of Pathology & Laboratory Medicine, 135, 799–802.
Kim, J., McCarthy, S. W., Thompson, J. F., Pupo, G. M., Vonthethoff, L., Nash, P., Mann, G. J., & Scolyer, R. A. (2012). Cellular blue nevus involving the urinary bladder. Pathology, 44, 664–668.
Nguyen, L. P., Emley, A., Wajapeyee, N., Green, M. R., & Mahalingam, M. (2010). BRAF V600E mutation and the tumour suppressor IGFBP7 in atypical genital naevi. British Journal of Dermatology, 162, 677–680.
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Portelli, F., Trambaiolo Antonelli, C., De Giorgi, V. (2020). Nevus. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4859
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4859
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